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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SORT1
All Species:
15.45
Human Site:
S756
Identified Species:
42.5
UniProt:
Q99523
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99523
NP_002950.3
831
92068
S756
K
Q
N
S
K
S
N
S
V
P
I
I
L
A
I
Chimpanzee
Pan troglodytes
XP_513621
404
45217
L334
S
N
S
V
P
I
I
L
A
I
V
G
L
M
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537041
826
91253
S751
K
Q
N
S
K
S
N
S
V
P
I
I
L
A
T
Cat
Felis silvestris
Mouse
Mus musculus
Q6PHU5
825
91182
S754
K
Q
N
S
K
S
N
S
V
P
I
I
L
A
I
Rat
Rattus norvegicus
O54861
825
91151
S754
K
Q
N
S
K
S
S
S
V
P
I
I
L
A
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505243
744
82822
L674
S
N
P
A
A
I
I
L
A
V
V
G
L
M
L
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001121210
801
89000
L727
I
K
V
P
T
S
S
L
V
P
V
I
I
S
V
Zebra Danio
Brachydanio rerio
Q6NUT7
814
90962
S740
T
K
E
H
S
F
N
S
A
P
I
I
A
V
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001185329
837
93762
K762
G
A
S
S
Q
N
K
K
S
H
S
A
A
F
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
48.6
N.A.
93
N.A.
90.8
90.9
N.A.
72.1
N.A.
60.4
61.4
N.A.
N.A.
N.A.
N.A.
34.7
Protein Similarity:
100
48.6
N.A.
95.7
N.A.
95
95.3
N.A.
80.3
N.A.
74.3
75.8
N.A.
N.A.
N.A.
N.A.
54.3
P-Site Identity:
100
6.6
N.A.
93.3
N.A.
100
93.3
N.A.
6.6
N.A.
26.6
33.3
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
26.6
N.A.
93.3
N.A.
100
100
N.A.
26.6
N.A.
66.6
46.6
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
0
12
12
0
0
0
34
0
0
12
23
45
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
12
0
0
0
0
0
0
0
12
0
% F
% Gly:
12
0
0
0
0
0
0
0
0
0
0
23
0
0
12
% G
% His:
0
0
0
12
0
0
0
0
0
12
0
0
0
0
0
% H
% Ile:
12
0
0
0
0
23
23
0
0
12
56
67
12
0
34
% I
% Lys:
45
23
0
0
45
0
12
12
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
34
0
0
0
0
67
0
23
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
23
0
% M
% Asn:
0
23
45
0
0
12
45
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
12
12
12
0
0
0
0
67
0
0
0
0
0
% P
% Gln:
0
45
0
0
12
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
23
0
23
56
12
56
23
56
12
0
12
0
0
12
0
% S
% Thr:
12
0
0
0
12
0
0
0
0
0
0
0
0
0
12
% T
% Val:
0
0
12
12
0
0
0
0
56
12
34
0
0
12
23
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _