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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GPER
All Species:
8.79
Human Site:
S50
Identified Species:
21.48
UniProt:
Q99527
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99527
NP_001035055.1
375
42248
S50
A
N
G
T
G
E
L
S
E
H
Q
Q
Y
V
I
Chimpanzee
Pan troglodytes
P55920
350
39800
G56
V
F
L
L
S
L
L
G
N
S
L
V
M
L
V
Rhesus Macaque
Macaca mulatta
Q2YEG0
351
39793
L56
L
V
F
L
L
S
L
L
G
N
S
L
V
M
L
Dog
Lupus familis
XP_537923
370
41869
Y50
E
L
S
E
H
Q
Q
Y
V
I
G
L
F
L
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8BMP4
375
42426
S50
G
N
L
T
G
D
L
S
E
H
Q
Q
Y
V
I
Rat
Rattus norvegicus
O08878
375
42241
S50
G
N
L
T
G
D
L
S
E
H
Q
Q
Y
V
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516051
376
42850
E51
N
I
S
H
D
K
S
E
E
H
R
Q
Y
V
I
Chicken
Gallus gallus
NP_001155877
357
40874
F62
I
F
L
F
P
I
G
F
V
G
N
I
L
I
L
Frog
Xenopus laevis
P35373
363
41522
V52
V
F
G
N
S
L
V
V
I
V
I
Y
S
Y
M
Zebra Danio
Brachydanio rerio
NP_001122195
353
40840
L54
S
C
L
Y
T
I
F
L
F
P
I
G
F
I
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
28.7
28.7
88.5
N.A.
86.6
86.1
N.A.
78.1
74.1
25
63.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
48.2
48
93
N.A.
91.7
91.1
N.A.
86.6
82.4
46.9
75.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
6.6
0
N.A.
80
80
N.A.
40
0
6.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
26.6
20
N.A.
86.6
86.6
N.A.
53.3
13.3
20
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
20
0
0
0
0
0
0
0
0
0
% D
% Glu:
10
0
0
10
0
10
0
10
40
0
0
0
0
0
0
% E
% Phe:
0
30
10
10
0
0
10
10
10
0
0
0
20
0
0
% F
% Gly:
20
0
20
0
30
0
10
10
10
10
10
10
0
0
10
% G
% His:
0
0
0
10
10
0
0
0
0
40
0
0
0
0
0
% H
% Ile:
10
10
0
0
0
20
0
0
10
10
20
10
0
20
40
% I
% Lys:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% K
% Leu:
10
10
50
20
10
20
50
20
0
0
10
20
10
20
20
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
10
10
10
% M
% Asn:
10
30
0
10
0
0
0
0
10
10
10
0
0
0
0
% N
% Pro:
0
0
0
0
10
0
0
0
0
10
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
10
10
0
0
0
30
40
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% R
% Ser:
10
0
20
0
20
10
10
30
0
10
10
0
10
0
10
% S
% Thr:
0
0
0
30
10
0
0
0
0
0
0
0
0
0
0
% T
% Val:
20
10
0
0
0
0
10
10
20
10
0
10
10
40
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
10
0
0
0
10
40
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _