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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LGMN All Species: 14.24
Human Site: S359 Identified Species: 24.1
UniProt: Q99538 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99538 NP_001008530.1 433 49411 S359 I V S L L A A S E A E V E Q L
Chimpanzee Pan troglodytes XP_001147732 433 49378 S359 I V S L L A A S E A E V E Q L
Rhesus Macaque Macaca mulatta XP_001092047 426 48206 V353 E K S V H K I V S L L A A S E
Dog Lupus familis XP_537355 433 49438 S359 M V S L M A S S D A E A K W L
Cat Felis silvestris
Mouse Mus musculus O89017 435 49354 F361 I V S L L A G F G E T A E R H
Rat Rattus norvegicus Q9R0J8 435 49448 F361 I V S L L A G F G E T A Q K H
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_421328 431 49243 S358 I V T L I T G S T E L T N Q I
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_999924 438 49173 D364 I V E H V V Q D K E E V Q D Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8T4E1 355 40350 I282 V C P K R V C I S T V G V R K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P49048 319 36399 T245 I D R Y T H Y T V N F L T K E
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002324151 489 53921 I402 I G K L L F G I E K A S E V L
Maize Zea mays NP_001105613 485 53399 S398 I G S L L F G S E D G P R V L
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q39119 494 54317 I407 V G K I L F G I S R G P E V L
Baker's Yeast Sacchar. cerevisiae P49018 411 47384 L337 L N N N V L D L A L E T Y R K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 91.4 83.3 N.A. 82.9 82.7 N.A. N.A. 72.7 N.A. 65.7 N.A. 26.3 N.A. 22.6 N.A.
Protein Similarity: 100 99.5 92.3 92.1 N.A. 91.2 91.4 N.A. N.A. 84.9 N.A. 76.9 N.A. 43.1 N.A. 40.1 N.A.
P-Site Identity: 100 100 6.6 53.3 N.A. 46.6 40 N.A. N.A. 33.3 N.A. 26.6 N.A. 0 N.A. 6.6 N.A.
P-Site Similarity: 100 100 13.3 86.6 N.A. 53.3 53.3 N.A. N.A. 53.3 N.A. 46.6 N.A. 13.3 N.A. 26.6 N.A.
Percent
Protein Identity: 38.6 36.7 N.A. 36.6 23.3 N.A.
Protein Similarity: 52.3 51.3 N.A. 51.4 45.2 N.A.
P-Site Identity: 40 46.6 N.A. 20 6.6 N.A.
P-Site Similarity: 40 46.6 N.A. 33.3 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 36 15 0 8 22 8 29 8 0 0 % A
% Cys: 0 8 0 0 0 0 8 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 0 0 8 8 8 8 0 0 0 8 0 % D
% Glu: 8 0 8 0 0 0 0 0 29 29 36 0 36 0 15 % E
% Phe: 0 0 0 0 0 22 0 15 0 0 8 0 0 0 0 % F
% Gly: 0 22 0 0 0 0 43 0 15 0 15 8 0 0 0 % G
% His: 0 0 0 8 8 8 0 0 0 0 0 0 0 0 15 % H
% Ile: 65 0 0 8 8 0 8 22 0 0 0 0 0 0 8 % I
% Lys: 0 8 15 8 0 8 0 0 8 8 0 0 8 15 15 % K
% Leu: 8 0 0 58 50 8 0 8 0 15 15 8 0 0 43 % L
% Met: 8 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 8 8 0 0 0 0 0 8 0 0 8 0 0 % N
% Pro: 0 0 8 0 0 0 0 0 0 0 0 15 0 0 0 % P
% Gln: 0 0 0 0 0 0 8 0 0 0 0 0 15 22 0 % Q
% Arg: 0 0 8 0 8 0 0 0 0 8 0 0 8 22 0 % R
% Ser: 0 0 50 0 0 0 8 36 22 0 0 8 0 8 0 % S
% Thr: 0 0 8 0 8 8 0 8 8 8 15 15 8 0 0 % T
% Val: 15 50 0 8 15 15 0 8 8 0 8 22 8 22 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % W
% Tyr: 0 0 0 8 0 0 8 0 0 0 0 0 8 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _