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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LGMN All Species: 19.39
Human Site: T322 Identified Species: 32.82
UniProt: Q99538 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99538 NP_001008530.1 433 49411 T322 M K R K L M N T N D L E E S R
Chimpanzee Pan troglodytes XP_001147732 433 49378 T322 M K R K L M N T N D L E E S R
Rhesus Macaque Macaca mulatta XP_001092047 426 48206 R317 V P L T I M K R K L M N T N D
Dog Lupus familis XP_537355 433 49438 T322 M K R K L M S T N D L Q E S R
Cat Felis silvestris
Mouse Mus musculus O89017 435 49354 T324 L K R K L L R T N D V K E S Q
Rat Rattus norvegicus Q9R0J8 435 49448 T324 L K R K L L R T N N M K E S Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_421328 431 49243 N322 K R K L M A T N D M Y E A K K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_999924 438 49173 L324 L A I L K R K L Q K T N D V D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8T4E1 355 40350 M246 D P S I G V Y M I D R Y T Y Y
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P49048 319 36399 S209 S M Y E W I D S P N V L S L S
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002324151 489 53921 V355 N Q R D A D L V H F W D K Y R
Maize Zea mays NP_001105613 485 53399 L350 V N Q R D A D L V Y F W Q K Y
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q39119 494 54317 V360 N Q R D A D L V H F W E K Y R
Baker's Yeast Sacchar. cerevisiae P49018 411 47384 N299 L I T D F F A N V Q N V I P D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 91.4 83.3 N.A. 82.9 82.7 N.A. N.A. 72.7 N.A. 65.7 N.A. 26.3 N.A. 22.6 N.A.
Protein Similarity: 100 99.5 92.3 92.1 N.A. 91.2 91.4 N.A. N.A. 84.9 N.A. 76.9 N.A. 43.1 N.A. 40.1 N.A.
P-Site Identity: 100 100 6.6 86.6 N.A. 60 53.3 N.A. N.A. 6.6 N.A. 0 N.A. 6.6 N.A. 0 N.A.
P-Site Similarity: 100 100 33.3 100 N.A. 93.3 93.3 N.A. N.A. 40 N.A. 13.3 N.A. 13.3 N.A. 40 N.A.
Percent
Protein Identity: 38.6 36.7 N.A. 36.6 23.3 N.A.
Protein Similarity: 52.3 51.3 N.A. 51.4 45.2 N.A.
P-Site Identity: 13.3 0 N.A. 20 0 N.A.
P-Site Similarity: 40 33.3 N.A. 40 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 15 15 8 0 0 0 0 0 8 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 0 22 8 15 15 0 8 36 0 8 8 0 22 % D
% Glu: 0 0 0 8 0 0 0 0 0 0 0 29 36 0 0 % E
% Phe: 0 0 0 0 8 8 0 0 0 15 8 0 0 0 0 % F
% Gly: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 15 0 0 0 0 0 0 % H
% Ile: 0 8 8 8 8 8 0 0 8 0 0 0 8 0 0 % I
% Lys: 8 36 8 36 8 0 15 0 8 8 0 15 15 15 8 % K
% Leu: 29 0 8 15 36 15 15 15 0 8 22 8 0 8 0 % L
% Met: 22 8 0 0 8 29 0 8 0 8 15 0 0 0 0 % M
% Asn: 15 8 0 0 0 0 15 15 36 15 8 15 0 8 0 % N
% Pro: 0 15 0 0 0 0 0 0 8 0 0 0 0 8 0 % P
% Gln: 0 15 8 0 0 0 0 0 8 8 0 8 8 0 15 % Q
% Arg: 0 8 50 8 0 8 15 8 0 0 8 0 0 0 36 % R
% Ser: 8 0 8 0 0 0 8 8 0 0 0 0 8 36 8 % S
% Thr: 0 0 8 8 0 0 8 36 0 0 8 0 15 0 0 % T
% Val: 15 0 0 0 0 8 0 15 15 0 15 8 0 8 0 % V
% Trp: 0 0 0 0 8 0 0 0 0 0 15 8 0 0 0 % W
% Tyr: 0 0 8 0 0 0 8 0 0 8 8 8 0 22 15 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _