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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LGMN
All Species:
28.18
Human Site:
Y221
Identified Species:
47.69
UniProt:
Q99538
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99538
NP_001008530.1
433
49411
Y221
E
S
S
Y
A
C
Y
Y
D
E
K
R
S
T
Y
Chimpanzee
Pan troglodytes
XP_001147732
433
49378
Y221
E
S
S
Y
A
C
Y
Y
D
E
K
R
S
T
Y
Rhesus Macaque
Macaca mulatta
XP_001092047
426
48206
S216
A
A
N
P
R
E
S
S
Y
A
C
Y
Y
D
E
Dog
Lupus familis
XP_537355
433
49438
Y221
E
S
S
Y
A
C
Y
Y
D
E
K
R
S
T
F
Cat
Felis silvestris
Mouse
Mus musculus
O89017
435
49354
Y223
E
S
S
Y
A
C
Y
Y
D
E
E
R
G
T
Y
Rat
Rattus norvegicus
Q9R0J8
435
49448
Y223
E
S
S
Y
A
C
Y
Y
D
E
E
R
S
T
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_421328
431
49243
Y221
E
S
S
Y
A
C
Y
Y
D
D
E
R
Q
T
Y
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_999924
438
49173
Y223
E
S
S
Y
A
C
Y
Y
D
E
A
R
D
T
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8T4E1
355
40350
A145
G
R
T
Q
N
G
T
A
R
S
K
K
L
L
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P49048
319
36399
D108
G
T
N
L
Y
G
S
D
V
E
V
D
Y
R
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002324151
489
53921
P254
C
P
G
E
N
P
S
P
P
P
E
Y
E
T
C
Maize
Zea mays
NP_001105613
485
53399
P249
C
P
G
E
F
P
S
P
P
P
E
Y
D
T
C
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39119
494
54317
P259
C
P
G
E
E
P
S
P
P
P
E
Y
E
T
C
Baker's Yeast
Sacchar. cerevisiae
P49018
411
47384
T198
E
I
F
F
M
I
D
T
C
Q
A
N
T
M
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
91.4
83.3
N.A.
82.9
82.7
N.A.
N.A.
72.7
N.A.
65.7
N.A.
26.3
N.A.
22.6
N.A.
Protein Similarity:
100
99.5
92.3
92.1
N.A.
91.2
91.4
N.A.
N.A.
84.9
N.A.
76.9
N.A.
43.1
N.A.
40.1
N.A.
P-Site Identity:
100
100
0
93.3
N.A.
86.6
93.3
N.A.
N.A.
80
N.A.
86.6
N.A.
6.6
N.A.
6.6
N.A.
P-Site Similarity:
100
100
13.3
100
N.A.
93.3
100
N.A.
N.A.
93.3
N.A.
86.6
N.A.
20
N.A.
20
N.A.
Percent
Protein Identity:
38.6
36.7
N.A.
36.6
23.3
N.A.
Protein Similarity:
52.3
51.3
N.A.
51.4
45.2
N.A.
P-Site Identity:
6.6
6.6
N.A.
6.6
13.3
N.A.
P-Site Similarity:
13.3
13.3
N.A.
13.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
50
0
0
8
0
8
15
0
0
0
0
% A
% Cys:
22
0
0
0
0
50
0
0
8
0
8
0
0
0
22
% C
% Asp:
0
0
0
0
0
0
8
8
50
8
0
8
15
8
0
% D
% Glu:
58
0
0
22
8
8
0
0
0
50
43
0
15
0
8
% E
% Phe:
0
0
8
8
8
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
15
0
22
0
0
15
0
0
0
0
0
0
8
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
8
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
29
8
0
0
0
% K
% Leu:
0
0
0
8
0
0
0
0
0
0
0
0
8
8
0
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
0
15
0
15
0
0
0
0
0
0
8
0
0
0
% N
% Pro:
0
22
0
8
0
22
0
22
22
22
0
0
0
0
0
% P
% Gln:
0
0
0
8
0
0
0
0
0
8
0
0
8
0
0
% Q
% Arg:
0
8
0
0
8
0
0
0
8
0
0
50
0
8
0
% R
% Ser:
0
50
50
0
0
0
36
8
0
8
0
0
29
0
8
% S
% Thr:
0
8
8
0
0
0
8
8
0
0
0
0
8
72
0
% T
% Val:
0
0
0
0
0
0
0
0
8
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
50
8
0
50
50
8
0
0
29
15
0
50
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _