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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LGMN All Species: 38.18
Human Site: Y233 Identified Species: 64.62
UniProt: Q99538 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99538 NP_001008530.1 433 49411 Y233 S T Y L G D W Y S V N W M E D
Chimpanzee Pan troglodytes XP_001147732 433 49378 Y233 S T Y L G D W Y S V N W M E D
Rhesus Macaque Macaca mulatta XP_001092047 426 48206 Y228 Y D E K R S T Y L G D W Y S V
Dog Lupus familis XP_537355 433 49438 Y233 S T F L G D W Y S V N W M E D
Cat Felis silvestris
Mouse Mus musculus O89017 435 49354 Y235 G T Y L G D W Y S V N W M E D
Rat Rattus norvegicus Q9R0J8 435 49448 Y235 S T Y L G D W Y S V N W M E D
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_421328 431 49243 Y233 Q T Y L G D W Y S V N W M E D
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_999924 438 49173 Y235 D T Y L G D W Y S V N W M E D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8T4E1 355 40350 N157 L L S D A G S N V L I Y L T G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P49048 319 36399 V120 Y R G E E V T V E S F I R V L
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002324151 489 53921 Y266 E T C L G D L Y S V A W M E D
Maize Zea mays NP_001105613 485 53399 Y261 D T C L G D L Y S V A W M E D
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q39119 494 54317 Y271 E T C L G D L Y S V A W M E D
Baker's Yeast Sacchar. cerevisiae P49018 411 47384 S210 T M Y S K F Y S P N I L A V G
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 91.4 83.3 N.A. 82.9 82.7 N.A. N.A. 72.7 N.A. 65.7 N.A. 26.3 N.A. 22.6 N.A.
Protein Similarity: 100 99.5 92.3 92.1 N.A. 91.2 91.4 N.A. N.A. 84.9 N.A. 76.9 N.A. 43.1 N.A. 40.1 N.A.
P-Site Identity: 100 100 13.3 93.3 N.A. 93.3 100 N.A. N.A. 93.3 N.A. 93.3 N.A. 0 N.A. 0 N.A.
P-Site Similarity: 100 100 20 100 N.A. 93.3 100 N.A. N.A. 93.3 N.A. 93.3 N.A. 20 N.A. 0 N.A.
Percent
Protein Identity: 38.6 36.7 N.A. 36.6 23.3 N.A.
Protein Similarity: 52.3 51.3 N.A. 51.4 45.2 N.A.
P-Site Identity: 73.3 73.3 N.A. 73.3 6.6 N.A.
P-Site Similarity: 73.3 73.3 N.A. 73.3 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 8 0 0 0 0 0 22 0 8 0 0 % A
% Cys: 0 0 22 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 15 8 0 8 0 72 0 0 0 0 8 0 0 0 72 % D
% Glu: 15 0 8 8 8 0 0 0 8 0 0 0 0 72 0 % E
% Phe: 0 0 8 0 0 8 0 0 0 0 8 0 0 0 0 % F
% Gly: 8 0 8 0 72 8 0 0 0 8 0 0 0 0 15 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 15 8 0 0 0 % I
% Lys: 0 0 0 8 8 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 8 8 0 72 0 0 22 0 8 8 0 8 8 0 8 % L
% Met: 0 8 0 0 0 0 0 0 0 0 0 0 72 0 0 % M
% Asn: 0 0 0 0 0 0 0 8 0 8 50 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % P
% Gln: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 8 0 0 8 0 0 0 0 0 0 0 8 0 0 % R
% Ser: 29 0 8 8 0 8 8 8 72 8 0 0 0 8 0 % S
% Thr: 8 72 0 0 0 0 15 0 0 0 0 0 0 8 0 % T
% Val: 0 0 0 0 0 8 0 8 8 72 0 0 0 15 8 % V
% Trp: 0 0 0 0 0 0 50 0 0 0 0 79 0 0 0 % W
% Tyr: 15 0 50 0 0 0 8 79 0 0 0 8 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _