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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MMP19
All Species:
22.73
Human Site:
S64
Identified Species:
45.45
UniProt:
Q99542
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99542
NP_002420.1
508
57357
S64
L
R
A
F
Q
E
A
S
E
L
P
V
S
G
Q
Chimpanzee
Pan troglodytes
XP_001154045
470
52999
F48
P
L
E
G
S
N
N
F
K
P
E
D
I
T
E
Rhesus Macaque
Macaca mulatta
XP_001111624
508
57284
S64
L
R
A
F
Q
E
A
S
E
L
P
V
S
G
Q
Dog
Lupus familis
XP_848410
547
61550
S65
L
R
T
F
Q
E
A
S
E
L
P
V
S
G
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9JHI0
527
59104
S65
L
R
T
F
Q
E
A
S
G
L
P
I
S
G
Q
Rat
Rattus norvegicus
Q99PW6
618
70447
Y91
V
S
T
M
Q
Q
F
Y
G
I
P
V
T
G
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512754
558
61524
S62
L
R
S
F
Q
E
A
S
E
L
P
V
T
G
W
Chicken
Gallus gallus
XP_415771
498
56504
S64
L
R
D
F
Q
R
V
S
H
L
R
P
S
G
V
Frog
Xenopus laevis
Q10835
469
53622
S46
Y
L
N
R
L
Y
S
S
S
S
N
P
V
G
M
Zebra Danio
Brachydanio rerio
XP_001337581
501
56922
P57
F
Q
W
L
S
W
L
P
V
T
G
H
L
D
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393358
568
63683
F78
A
I
S
E
F
Q
A
F
A
G
L
N
I
T
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001028820
562
62609
M81
I
R
N
M
Q
R
Y
M
D
V
P
L
T
G
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.7
94.4
79.3
N.A.
76.6
32
N.A.
58.2
36.8
34.2
35.4
N.A.
N.A.
34.3
N.A.
35
Protein Similarity:
100
91.3
97.2
84
N.A.
85.3
46.7
N.A.
68.6
50.5
46.2
51.9
N.A.
N.A.
50.8
N.A.
49.8
P-Site Identity:
100
0
100
93.3
N.A.
80
26.6
N.A.
80
53.3
13.3
0
N.A.
N.A.
6.6
N.A.
26.6
P-Site Similarity:
100
13.3
100
93.3
N.A.
86.6
53.3
N.A.
93.3
53.3
20
6.6
N.A.
N.A.
20
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
17
0
0
0
50
0
9
0
0
0
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
0
0
0
0
0
9
0
0
9
0
9
0
% D
% Glu:
0
0
9
9
0
42
0
0
34
0
9
0
0
0
9
% E
% Phe:
9
0
0
50
9
0
9
17
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
9
0
0
0
0
17
9
9
0
0
75
9
% G
% His:
0
0
0
0
0
0
0
0
9
0
0
9
0
0
9
% H
% Ile:
9
9
0
0
0
0
0
0
0
9
0
9
17
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% K
% Leu:
50
17
0
9
9
0
9
0
0
50
9
9
9
0
0
% L
% Met:
0
0
0
17
0
0
0
9
0
0
0
0
0
0
9
% M
% Asn:
0
0
17
0
0
9
9
0
0
0
9
9
0
0
0
% N
% Pro:
9
0
0
0
0
0
0
9
0
9
59
17
0
0
0
% P
% Gln:
0
9
0
0
67
17
0
0
0
0
0
0
0
0
34
% Q
% Arg:
0
59
0
9
0
17
0
0
0
0
9
0
0
0
0
% R
% Ser:
0
9
17
0
17
0
9
59
9
9
0
0
42
0
0
% S
% Thr:
0
0
25
0
0
0
0
0
0
9
0
0
25
17
0
% T
% Val:
9
0
0
0
0
0
9
0
9
9
0
42
9
0
17
% V
% Trp:
0
0
9
0
0
9
0
0
0
0
0
0
0
0
9
% W
% Tyr:
9
0
0
0
0
9
9
9
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _