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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MMP19
All Species:
26.36
Human Site:
Y234
Identified Species:
52.73
UniProt:
Q99542
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99542
NP_002420.1
508
57357
Y234
Q
A
L
M
A
P
V
Y
E
G
Y
R
P
H
F
Chimpanzee
Pan troglodytes
XP_001154045
470
52999
V204
T
E
G
T
Y
H
G
V
N
L
R
I
I
A
A
Rhesus Macaque
Macaca mulatta
XP_001111624
508
57284
Y234
Q
A
L
M
A
P
V
Y
Q
G
Y
Q
P
H
F
Dog
Lupus familis
XP_848410
547
61550
Y235
Q
A
L
M
A
P
V
Y
A
G
Y
R
P
H
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9JHI0
527
59104
Y235
Q
A
L
M
A
P
V
Y
A
G
Y
Q
P
F
F
Rat
Rattus norvegicus
Q99PW6
618
70447
Y277
S
A
I
M
A
P
F
Y
Q
Y
M
E
T
H
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512754
558
61524
Y232
K
A
L
M
A
P
V
Y
L
G
Y
R
P
D
F
Chicken
Gallus gallus
XP_415771
498
56504
T231
L
G
L
E
H
S
P
T
K
S
A
L
M
S
P
Frog
Xenopus laevis
Q10835
469
53622
E203
D
T
H
F
D
D
D
E
M
F
S
T
D
N
K
Zebra Danio
Brachydanio rerio
XP_001337581
501
56922
H227
V
T
A
H
E
I
G
H
T
L
G
L
V
H
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393358
568
63683
Y253
S
A
L
M
A
P
F
Y
R
G
Y
E
P
Y
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001028820
562
62609
Y267
R
A
L
M
A
P
F
Y
A
G
Y
I
P
D
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.7
94.4
79.3
N.A.
76.6
32
N.A.
58.2
36.8
34.2
35.4
N.A.
N.A.
34.3
N.A.
35
Protein Similarity:
100
91.3
97.2
84
N.A.
85.3
46.7
N.A.
68.6
50.5
46.2
51.9
N.A.
N.A.
50.8
N.A.
49.8
P-Site Identity:
100
0
86.6
93.3
N.A.
80
40
N.A.
80
6.6
0
6.6
N.A.
N.A.
66.6
N.A.
66.6
P-Site Similarity:
100
0
100
93.3
N.A.
86.6
53.3
N.A.
86.6
13.3
6.6
13.3
N.A.
N.A.
73.3
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
67
9
0
67
0
0
0
25
0
9
0
0
9
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
9
9
9
0
0
0
0
0
9
17
0
% D
% Glu:
0
9
0
9
9
0
0
9
9
0
0
17
0
0
0
% E
% Phe:
0
0
0
9
0
0
25
0
0
9
0
0
0
9
59
% F
% Gly:
0
9
9
0
0
0
17
0
0
59
9
0
0
0
0
% G
% His:
0
0
9
9
9
9
0
9
0
0
0
0
0
42
0
% H
% Ile:
0
0
9
0
0
9
0
0
0
0
0
17
9
0
0
% I
% Lys:
9
0
0
0
0
0
0
0
9
0
0
0
0
0
9
% K
% Leu:
9
0
67
0
0
0
0
0
9
17
0
17
0
0
0
% L
% Met:
0
0
0
67
0
0
0
0
9
0
9
0
9
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
9
0
0
0
0
9
9
% N
% Pro:
0
0
0
0
0
67
9
0
0
0
0
0
59
0
9
% P
% Gln:
34
0
0
0
0
0
0
0
17
0
0
17
0
0
0
% Q
% Arg:
9
0
0
0
0
0
0
0
9
0
9
25
0
0
0
% R
% Ser:
17
0
0
0
0
9
0
0
0
9
9
0
0
9
9
% S
% Thr:
9
17
0
9
0
0
0
9
9
0
0
9
9
0
0
% T
% Val:
9
0
0
0
0
0
42
9
0
0
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
0
0
67
0
9
59
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _