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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MPHOSPH6
All Species:
8.79
Human Site:
T147
Identified Species:
16.11
UniProt:
Q99547
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99547
NP_005783
160
18996
T147
E
D
E
N
G
D
I
T
P
I
K
A
K
K
M
Chimpanzee
Pan troglodytes
XP_511131
160
18980
T147
E
D
E
N
G
D
I
T
P
I
K
A
K
K
M
Rhesus Macaque
Macaca mulatta
XP_001111939
160
19004
K147
E
D
E
N
G
D
I
K
P
I
K
A
K
K
M
Dog
Lupus familis
XP_536767
161
19124
K147
E
D
E
N
G
H
I
K
P
T
V
K
V
K
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9D1Q1
161
19067
K148
E
D
E
N
G
T
I
K
A
I
K
P
K
K
M
Rat
Rattus norvegicus
NP_001123353
161
19084
K148
E
D
E
N
G
N
I
K
A
I
K
T
K
K
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508366
152
17890
S141
D
N
G
N
L
G
P
S
K
A
K
K
T
F
L
Chicken
Gallus gallus
XP_414172
261
29249
S245
D
E
D
E
E
E
N
S
N
T
K
P
K
K
A
Frog
Xenopus laevis
NP_001090153
164
19467
N147
K
D
E
E
E
D
E
N
C
N
I
R
S
S
K
Zebra Danio
Brachydanio rerio
NP_001003618
168
19793
N152
N
K
E
D
V
N
C
N
V
T
D
D
I
R
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523609
162
18450
P146
I
G
G
D
S
D
S
P
H
A
M
K
K
Q
Y
Honey Bee
Apis mellifera
XP_001122030
111
13233
D104
Q
K
E
T
D
I
S
D
E
Q
M
A
K
R
N
Nematode Worm
Caenorhab. elegans
O16207
189
21634
F160
E
T
T
G
G
R
R
F
N
I
K
D
I
R
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
98.7
91.3
N.A.
86.9
87.5
N.A.
73.7
48.2
68.9
62.5
N.A.
30.8
31.2
31.7
N.A.
Protein Similarity:
100
99.3
99.3
94.4
N.A.
93.7
95
N.A.
80
56.3
83.5
82.1
N.A.
52.4
49.3
49.2
N.A.
P-Site Identity:
100
100
93.3
53.3
N.A.
73.3
73.3
N.A.
13.3
20
20
6.6
N.A.
13.3
20
26.6
N.A.
P-Site Similarity:
100
100
93.3
53.3
N.A.
73.3
80
N.A.
40
53.3
26.6
26.6
N.A.
26.6
33.3
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
16
16
0
31
0
0
8
% A
% Cys:
0
0
0
0
0
0
8
0
8
0
0
0
0
0
0
% C
% Asp:
16
54
8
16
8
39
0
8
0
0
8
16
0
0
0
% D
% Glu:
54
8
70
16
16
8
8
0
8
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
8
0
% F
% Gly:
0
8
16
8
54
8
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
8
0
0
8
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
8
47
0
0
47
8
0
16
0
0
% I
% Lys:
8
16
0
0
0
0
0
31
8
0
62
24
62
54
24
% K
% Leu:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
16
0
0
0
39
% M
% Asn:
8
8
0
54
0
16
8
16
16
8
0
0
0
0
8
% N
% Pro:
0
0
0
0
0
0
8
8
31
0
0
16
0
0
8
% P
% Gln:
8
0
0
0
0
0
0
0
0
8
0
0
0
8
0
% Q
% Arg:
0
0
0
0
0
8
8
0
0
0
0
8
0
24
0
% R
% Ser:
0
0
0
0
8
0
16
16
0
0
0
0
8
8
0
% S
% Thr:
0
8
8
8
0
8
0
16
0
24
0
8
8
0
0
% T
% Val:
0
0
0
0
8
0
0
0
8
0
8
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _