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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAP3K14
All Species:
8.18
Human Site:
S758
Identified Species:
30
UniProt:
Q99558
Number Species:
6
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99558
NP_003945.2
947
104042
S758
A
P
A
R
N
P
S
S
P
E
R
K
A
T
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001115538
947
104061
S758
A
P
A
R
N
P
S
S
P
E
R
K
A
T
F
Dog
Lupus familis
XP_548049
955
104667
S766
T
P
A
K
N
P
S
S
A
E
R
K
A
T
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9WUL6
942
103061
F753
A
T
A
K
G
P
S
F
P
D
R
R
A
T
L
Rat
Rattus norvegicus
NP_001101771
942
103566
L753
A
P
A
K
G
P
S
L
P
D
R
R
A
T
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515861
418
45090
P242
W
R
G
E
Y
R
E
P
R
R
L
A
V
N
A
Chicken
Gallus gallus
NP_001026098
909
100834
R733
N
A
S
R
E
L
S
R
I
W
D
P
P
P
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.1
88.6
N.A.
84.4
85.2
N.A.
32.3
58.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
98.6
92.7
N.A.
90
90.3
N.A.
36.4
70
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
93.3
73.3
N.A.
53.3
60
N.A.
0
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
93.3
86.6
N.A.
80
80
N.A.
0
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
58
15
72
0
0
0
0
0
15
0
0
15
72
0
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
29
15
0
0
0
0
% D
% Glu:
0
0
0
15
15
0
15
0
0
43
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
15
0
0
0
0
0
0
29
% F
% Gly:
0
0
15
0
29
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
15
0
0
0
0
0
0
% I
% Lys:
0
0
0
43
0
0
0
0
0
0
0
43
0
0
0
% K
% Leu:
0
0
0
0
0
15
0
15
0
0
15
0
0
0
43
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
15
0
0
0
43
0
0
0
0
0
0
0
0
15
0
% N
% Pro:
0
58
0
0
0
72
0
15
58
0
0
15
15
15
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
15
0
43
0
15
0
15
15
15
72
29
0
0
0
% R
% Ser:
0
0
15
0
0
0
86
43
0
0
0
0
0
0
0
% S
% Thr:
15
15
0
0
0
0
0
0
0
0
0
0
0
72
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
15
0
15
% V
% Trp:
15
0
0
0
0
0
0
0
0
15
0
0
0
0
0
% W
% Tyr:
0
0
0
0
15
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _