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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NUP88 All Species: 4.55
Human Site: S606 Identified Species: 10
UniProt: Q99567 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.3
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99567 NP_002523.2 741 83542 S606 K K Q L E D L S Y C R E E R K
Chimpanzee Pan troglodytes XP_001165761 741 83546 S606 K K Q L E D L S Y C R E E R K
Rhesus Macaque Macaca mulatta XP_001100662 741 83680 N606 K K Q L E D L N Y C R E E R K
Dog Lupus familis XP_848977 459 50145 I358 W D S R A D I I P S L Y V F E
Cat Felis silvestris
Mouse Mus musculus Q8CEC0 753 84919 R618 L N Y C R E E R V S H L F R K
Rat Rattus norvegicus O08658 742 83567 N607 R K Q L E D L N Y C R E E R K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515316 322 34579 L221 E L E L A L K L A A G E D D D
Chicken Gallus gallus
Frog Xenopus laevis NP_001084403 728 82451 R593 E K Q L E D L R Y C R E E R K
Zebra Danio Brachydanio rerio NP_001018302 720 80770 A585 N K Q L E D L A L C R E D R K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9GYU8 702 78662 Q566 E Q Q L Q E I Q D L E Q E R E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_788920 618 68704 R517 K Q E E L L N R V S I V L H T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 96.6 54.9 N.A. 88.8 89.7 N.A. 22.8 N.A. 64.3 63.1 N.A. 27.1 N.A. N.A. 35
Protein Similarity: 100 99.4 98.1 58.2 N.A. 93.4 94.3 N.A. 29.4 N.A. 78 75.8 N.A. 48.9 N.A. N.A. 52
P-Site Identity: 100 100 93.3 6.6 N.A. 13.3 86.6 N.A. 13.3 N.A. 86.6 73.3 N.A. 26.6 N.A. N.A. 6.6
P-Site Similarity: 100 100 100 20 N.A. 20 100 N.A. 33.3 N.A. 93.3 86.6 N.A. 73.3 N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 19 0 0 10 10 10 0 0 0 0 0 % A
% Cys: 0 0 0 10 0 0 0 0 0 55 0 0 0 0 0 % C
% Asp: 0 10 0 0 0 64 0 0 10 0 0 0 19 10 10 % D
% Glu: 28 0 19 10 55 19 10 0 0 0 10 64 55 0 19 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 10 10 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 10 0 0 10 0 % H
% Ile: 0 0 0 0 0 0 19 10 0 0 10 0 0 0 0 % I
% Lys: 37 55 0 0 0 0 10 0 0 0 0 0 0 0 64 % K
% Leu: 10 10 0 73 10 19 55 10 10 10 10 10 10 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 10 0 0 0 0 10 19 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % P
% Gln: 0 19 64 0 10 0 0 10 0 0 0 10 0 0 0 % Q
% Arg: 10 0 0 10 10 0 0 28 0 0 55 0 0 73 0 % R
% Ser: 0 0 10 0 0 0 0 19 0 28 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % T
% Val: 0 0 0 0 0 0 0 0 19 0 0 10 10 0 0 % V
% Trp: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 10 0 0 0 0 0 46 0 0 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _