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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NUP88 All Species: 8.79
Human Site: S77 Identified Species: 19.33
UniProt: Q99567 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99567 NP_002523.2 741 83542 S77 L W D G E D S S F L V V R L R
Chimpanzee Pan troglodytes XP_001165761 741 83546 S77 L W D G E D S S F L V V R L R
Rhesus Macaque Macaca mulatta XP_001100662 741 83680 S77 L W D A E D S S F L V V R L R
Dog Lupus familis XP_848977 459 50145
Cat Felis silvestris
Mouse Mus musculus Q8CEC0 753 84919 A79 L W D A E G S A F L V V R L R
Rat Rattus norvegicus O08658 742 83567 A79 L W D A E G S A F L V V R L R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515316 322 34579
Chicken Gallus gallus
Frog Xenopus laevis NP_001084403 728 82451 A64 V W D A E E C A F H T V T L R
Zebra Danio Brachydanio rerio NP_001018302 720 80770 L64 S V F Y T T N L R Q L N S D G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9GYU8 702 78662 Q67 A K V N I Q F Q T L I P S S L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_788920 618 68704 L33 P C G Q N V L L Y G K R G A S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 96.6 54.9 N.A. 88.8 89.7 N.A. 22.8 N.A. 64.3 63.1 N.A. 27.1 N.A. N.A. 35
Protein Similarity: 100 99.4 98.1 58.2 N.A. 93.4 94.3 N.A. 29.4 N.A. 78 75.8 N.A. 48.9 N.A. N.A. 52
P-Site Identity: 100 100 93.3 0 N.A. 80 80 N.A. 0 N.A. 46.6 0 N.A. 6.6 N.A. N.A. 0
P-Site Similarity: 100 100 93.3 0 N.A. 86.6 86.6 N.A. 0 N.A. 66.6 13.3 N.A. 13.3 N.A. N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 37 0 0 0 28 0 0 0 0 0 10 0 % A
% Cys: 0 10 0 0 0 0 10 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 55 0 0 28 0 0 0 0 0 0 0 10 0 % D
% Glu: 0 0 0 0 55 10 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 10 0 0 0 10 0 55 0 0 0 0 0 0 % F
% Gly: 0 0 10 19 0 19 0 0 0 10 0 0 10 0 10 % G
% His: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % H
% Ile: 0 0 0 0 10 0 0 0 0 0 10 0 0 0 0 % I
% Lys: 0 10 0 0 0 0 0 0 0 0 10 0 0 0 0 % K
% Leu: 46 0 0 0 0 0 10 19 0 55 10 0 0 55 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 10 10 0 10 0 0 0 0 10 0 0 0 % N
% Pro: 10 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % P
% Gln: 0 0 0 10 0 10 0 10 0 10 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 10 0 0 10 46 0 55 % R
% Ser: 10 0 0 0 0 0 46 28 0 0 0 0 19 10 10 % S
% Thr: 0 0 0 0 10 10 0 0 10 0 10 0 10 0 0 % T
% Val: 10 10 10 0 0 10 0 0 0 0 46 55 0 0 0 % V
% Trp: 0 55 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 10 0 0 0 0 10 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _