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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
P2RX4
All Species:
34.24
Human Site:
T17
Identified Species:
75.33
UniProt:
Q99571
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99571
NP_002551.2
388
43369
T17
A
F
L
F
E
Y
D
T
P
R
I
V
L
I
R
Chimpanzee
Pan troglodytes
XP_001164210
404
45295
T17
A
F
L
F
E
Y
D
T
P
R
I
V
L
I
R
Rhesus Macaque
Macaca mulatta
XP_001090844
340
37778
Dog
Lupus familis
XP_543389
388
43458
T17
P
F
L
F
E
Y
D
T
P
R
I
V
L
I
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJX6
388
43419
T17
S
F
L
F
E
Y
D
T
P
R
I
V
L
I
R
Rat
Rattus norvegicus
P51577
388
43483
T17
S
F
L
F
E
Y
D
T
P
R
I
V
L
I
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519521
357
40415
Y9
V
F
L
W
E
K
G
Y
Q
E
T
D
S
V
V
Chicken
Gallus gallus
NP_989622
385
43311
T17
G
F
L
F
E
Y
D
T
P
R
I
V
L
I
R
Frog
Xenopus laevis
NP_001082067
391
44317
T19
S
C
L
F
D
Y
D
T
P
R
I
A
L
I
K
Zebra Danio
Brachydanio rerio
NP_705939
389
43939
T20
Q
C
F
F
D
Y
Y
T
S
K
I
L
I
I
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792184
418
46849
T35
A
S
F
F
E
Y
D
T
P
K
I
V
H
I
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96
77
89.9
N.A.
86.8
87.3
N.A.
46.9
75.7
69.3
58.8
N.A.
N.A.
N.A.
N.A.
46.6
Protein Similarity:
100
96
80.1
95.8
N.A.
94.5
94.3
N.A.
59.2
87.1
82.8
76.8
N.A.
N.A.
N.A.
N.A.
64.5
P-Site Identity:
100
100
0
93.3
N.A.
93.3
93.3
N.A.
20
93.3
66.6
40
N.A.
N.A.
N.A.
N.A.
66.6
P-Site Similarity:
100
100
0
93.3
N.A.
100
100
N.A.
33.3
93.3
86.6
66.6
N.A.
N.A.
N.A.
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
28
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% A
% Cys:
0
19
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
19
0
73
0
0
0
0
10
0
0
0
% D
% Glu:
0
0
0
0
73
0
0
0
0
10
0
0
0
0
0
% E
% Phe:
0
64
19
82
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
82
0
10
82
0
% I
% Lys:
0
0
0
0
0
10
0
0
0
19
0
0
0
0
19
% K
% Leu:
0
0
73
0
0
0
0
0
0
0
0
10
64
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
0
0
0
0
0
0
0
73
0
0
0
0
0
0
% P
% Gln:
10
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
64
0
0
0
0
64
% R
% Ser:
28
10
0
0
0
0
0
0
10
0
0
0
10
0
0
% S
% Thr:
0
0
0
0
0
0
0
82
0
0
10
0
0
0
0
% T
% Val:
10
0
0
0
0
0
0
0
0
0
0
64
0
10
10
% V
% Trp:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
82
10
10
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _