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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: POP1 All Species: 8.79
Human Site: S568 Identified Species: 24.17
UniProt: Q99575 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99575 NP_001139332.1 1024 114709 S568 S V T E N K I S D Q D L N R M
Chimpanzee Pan troglodytes XP_001149384 1024 114685 S568 S V T E N K I S D Q D L N R M
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_539099 1046 117190 S597 N V T K N K I S D Q D L N R K
Cat Felis silvestris
Mouse Mus musculus NP_080616 1015 114010 L568 S V T E N K L L D Q D L N R M
Rat Rattus norvegicus NP_001124022 1044 116616 V597 S V T E N K I V D Q D L N R M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521814 736 82555 P315 P V T F V W K P L D D P G V I
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001339421 365 41212
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572236 857 98808 M436 L S A G D L L M N Q P K S L P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q11188 752 87104 K331 W D R K T V L K H K K V N K E
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 N.A. 80.7 N.A. 77.3 76.5 N.A. 52.6 N.A. N.A. 20.8 N.A. 26.5 N.A. 21 N.A.
Protein Similarity: 100 99.4 N.A. 86.8 N.A. 85 84.5 N.A. 60.3 N.A. N.A. 26.8 N.A. 41.3 N.A. 37.7 N.A.
P-Site Identity: 100 100 N.A. 80 N.A. 86.6 93.3 N.A. 20 N.A. N.A. 0 N.A. 6.6 N.A. 6.6 N.A.
P-Site Similarity: 100 100 N.A. 93.3 N.A. 93.3 93.3 N.A. 26.6 N.A. N.A. 0 N.A. 33.3 N.A. 40 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 12 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 12 0 0 12 0 0 0 56 12 67 0 0 0 0 % D
% Glu: 0 0 0 45 0 0 0 0 0 0 0 0 0 0 12 % E
% Phe: 0 0 0 12 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 12 0 0 0 0 0 0 0 0 12 0 0 % G
% His: 0 0 0 0 0 0 0 0 12 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 45 0 0 0 0 0 0 0 12 % I
% Lys: 0 0 0 23 0 56 12 12 0 12 12 12 0 12 12 % K
% Leu: 12 0 0 0 0 12 34 12 12 0 0 56 0 12 0 % L
% Met: 0 0 0 0 0 0 0 12 0 0 0 0 0 0 45 % M
% Asn: 12 0 0 0 56 0 0 0 12 0 0 0 67 0 0 % N
% Pro: 12 0 0 0 0 0 0 12 0 0 12 12 0 0 12 % P
% Gln: 0 0 0 0 0 0 0 0 0 67 0 0 0 0 0 % Q
% Arg: 0 0 12 0 0 0 0 0 0 0 0 0 0 56 0 % R
% Ser: 45 12 0 0 0 0 0 34 0 0 0 0 12 0 0 % S
% Thr: 0 0 67 0 12 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 67 0 0 12 12 0 12 0 0 0 12 0 12 0 % V
% Trp: 12 0 0 0 0 12 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _