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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TSC22D3 All Species: 31.52
Human Site: T95 Identified Species: 86.67
UniProt: Q99576 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99576 NP_001015881.1 134 14810 T95 S Q L E R E N T L L K T L A S
Chimpanzee Pan troglodytes XP_001141188 176 19461 T137 S Q L E R E N T L L K T L A S
Rhesus Macaque Macaca mulatta XP_001095704 200 22222 T161 S Q L E R E N T L L K T L A S
Dog Lupus familis XP_549177 134 14927 T95 S Q L E R E N T L L K T L A S
Cat Felis silvestris
Mouse Mus musculus Q9Z2S7 137 15159 T95 S Q L E R E N T L L K T L A S
Rat Rattus norvegicus Q9EQZ1 134 14817 T95 S Q L E R E N T L L K T L A S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505336 139 15180 S95 S Q L E R E N S L L K T L A S
Chicken Gallus gallus
Frog Xenopus laevis NP_001080286 137 15407 H95 S Q L E K E N H L L K N L A S
Zebra Danio Brachydanio rerio NP_956863 143 15872 S95 N Q L E R E N S L L K N L A S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 60.2 53 94.7 N.A. 92.6 95.5 N.A. 84.1 N.A. 76.6 76.9 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 65.9 62 96.2 N.A. 96.3 98.5 N.A. 88.4 N.A. 83.9 84.6 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 93.3 N.A. 80 80 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 N.A. 86.6 93.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 100 0 100 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 12 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 12 0 0 0 0 0 100 0 0 0 0 % K
% Leu: 0 0 100 0 0 0 0 0 100 100 0 0 100 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 12 0 0 0 0 0 100 0 0 0 0 23 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 89 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 89 0 0 0 0 0 0 23 0 0 0 0 0 0 100 % S
% Thr: 0 0 0 0 0 0 0 67 0 0 0 78 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _