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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RIT2
All Species:
24.85
Human Site:
S186
Identified Species:
42.05
UniProt:
Q99578
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99578
NP_002921.1
217
24668
S186
R
E
I
R
K
K
E
S
M
P
S
L
M
E
K
Chimpanzee
Pan troglodytes
XP_001138470
242
27266
S186
R
E
I
R
K
K
E
S
M
P
S
S
M
D
K
Rhesus Macaque
Macaca mulatta
XP_001083497
217
24677
S186
R
E
I
R
K
K
E
S
M
P
S
L
M
E
K
Dog
Lupus familis
XP_537249
219
25045
E188
E
I
R
R
K
E
K
E
A
V
L
A
M
E
K
Cat
Felis silvestris
Mouse
Mus musculus
P70425
217
24784
S186
R
E
I
R
R
K
E
S
M
L
S
L
V
E
R
Rat
Rattus norvegicus
Q5BJQ5
217
24743
S186
R
E
I
R
R
K
E
S
M
L
S
L
V
E
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506896
217
24867
S186
R
E
I
R
K
K
E
S
S
L
S
L
M
E
K
Chicken
Gallus gallus
XP_001233997
217
24823
S186
R
E
I
R
R
K
E
S
S
L
T
V
A
E
K
Frog
Xenopus laevis
Q7ZXH7
184
20815
V154
S
A
K
S
K
I
N
V
N
E
I
F
Y
D
L
Zebra Danio
Brachydanio rerio
Q6TEN1
184
20809
V154
S
A
K
S
K
I
N
V
N
E
I
F
Y
D
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P08645
184
20845
N154
A
K
A
K
V
N
V
N
D
I
F
Y
D
L
V
Honey Bee
Apis mellifera
XP_395139
235
26905
R199
R
Q
I
R
A
K
E
R
S
R
N
S
V
R
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783565
275
31241
R188
R
E
I
R
K
K
E
R
A
E
I
Q
A
Q
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P01119
309
34328
N264
T
K
Y
S
S
N
G
N
G
N
R
S
D
I
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.7
99.5
66.6
N.A.
91.7
91.2
N.A.
89.4
80.6
40
40
N.A.
43.3
53.1
N.A.
45
Protein Similarity:
100
88.4
100
81.2
N.A.
96.3
95.8
N.A.
94.4
91.7
60.3
60.8
N.A.
62.2
67.6
N.A.
58.1
P-Site Identity:
100
86.6
100
33.3
N.A.
73.3
73.3
N.A.
86.6
60
6.6
6.6
N.A.
0
40
N.A.
46.6
P-Site Similarity:
100
93.3
100
46.6
N.A.
93.3
93.3
N.A.
86.6
80
13.3
13.3
N.A.
20
60
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
36.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
51.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
15
8
0
8
0
0
0
15
0
0
8
15
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
8
0
0
0
15
22
0
% D
% Glu:
8
58
0
0
0
8
65
8
0
22
0
0
0
50
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
8
15
0
0
0
% F
% Gly:
0
0
0
0
0
0
8
0
8
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
65
0
0
15
0
0
0
8
22
0
0
8
0
% I
% Lys:
0
15
15
8
58
65
8
0
0
0
0
0
0
0
50
% K
% Leu:
0
0
0
0
0
0
0
0
0
29
8
36
0
8
15
% L
% Met:
0
0
0
0
0
0
0
0
36
0
0
0
36
0
0
% M
% Asn:
0
0
0
0
0
15
15
15
15
8
8
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
22
0
0
0
0
0
% P
% Gln:
0
8
0
0
0
0
0
0
0
0
0
8
0
8
0
% Q
% Arg:
65
0
8
72
22
0
0
15
0
8
8
0
0
8
15
% R
% Ser:
15
0
0
22
8
0
0
50
22
0
43
22
0
0
8
% S
% Thr:
8
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% T
% Val:
0
0
0
0
8
0
8
15
0
8
0
8
22
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
0
0
0
0
8
15
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _