KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SFRS2IP
All Species:
9.39
Human Site:
S614
Identified Species:
29.52
UniProt:
Q99590
Number Species:
7
Phosphosite Substitution
Charge Score:
0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99590
NP_004710.2
1463
164652
S614
E
S
P
K
L
E
S
S
E
G
E
I
I
Q
T
Chimpanzee
Pan troglodytes
XP_001165201
1453
163512
S604
E
S
P
Q
L
E
S
S
G
G
E
I
I
Q
T
Rhesus Macaque
Macaca mulatta
XP_001093213
1438
161781
S605
E
S
P
K
L
K
S
S
E
G
E
I
I
Q
T
Dog
Lupus familis
XP_534828
1568
176331
S734
V
D
S
P
T
L
E
S
S
E
S
K
I
I
Q
Cat
Felis silvestris
Mouse
Mus musculus
NP_082424
1456
162081
I639
D
S
E
L
P
E
H
I
Q
T
E
N
T
E
I
Rat
Rattus norvegicus
Q63625
1685
184195
D842
P
F
D
P
T
G
S
D
S
S
P
P
S
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416047
1361
153147
E555
P
V
T
S
P
E
N
E
L
L
E
H
P
E
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_694845
1089
120657
Q283
E
K
R
E
D
E
E
Q
E
P
E
A
E
N
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
93.5
75.8
N.A.
67.8
20.6
N.A.
N.A.
50.7
N.A.
28.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.6
95.5
82.4
N.A.
78.6
35.9
N.A.
N.A.
65.8
N.A.
44.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
86.6
93.3
13.3
N.A.
20
6.6
N.A.
N.A.
13.3
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
100
13.3
N.A.
40
13.3
N.A.
N.A.
26.6
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
13
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
13
13
13
0
13
0
0
13
0
0
0
0
0
0
0
% D
% Glu:
50
0
13
13
0
63
25
13
38
13
75
0
13
25
0
% E
% Phe:
0
13
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
13
0
0
13
38
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
13
0
0
0
0
13
0
0
13
% H
% Ile:
0
0
0
0
0
0
0
13
0
0
0
38
50
13
13
% I
% Lys:
0
13
0
25
0
13
0
0
0
0
0
13
0
0
0
% K
% Leu:
0
0
0
13
38
13
0
0
13
13
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
13
0
0
0
0
13
0
13
0
% N
% Pro:
25
0
38
25
25
0
0
0
0
13
13
13
13
0
13
% P
% Gln:
0
0
0
13
0
0
0
13
13
0
0
0
0
38
13
% Q
% Arg:
0
0
13
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
50
13
13
0
0
50
50
25
13
13
0
13
13
13
% S
% Thr:
0
0
13
0
25
0
0
0
0
13
0
0
13
0
38
% T
% Val:
13
13
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _