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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TIMM17A
All Species:
31.82
Human Site:
T53
Identified Species:
50
UniProt:
Q99595
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99595
NP_006326.1
171
18024
T53
H
R
L
R
G
S
L
T
A
I
K
T
R
A
P
Chimpanzee
Pan troglodytes
XP_001148565
171
18082
T53
H
R
L
R
G
S
L
T
A
I
K
T
R
A
P
Rhesus Macaque
Macaca mulatta
XP_001108034
171
17995
T53
H
R
L
R
G
S
L
T
A
I
K
T
R
A
P
Dog
Lupus familis
XP_537124
171
17975
T53
H
R
L
R
G
S
L
T
A
I
K
T
R
A
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z0V8
171
18093
T53
H
R
L
R
G
S
L
T
A
I
K
T
R
A
P
Rat
Rattus norvegicus
O35092
171
18019
T53
H
R
L
R
G
S
L
T
A
I
K
T
R
A
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508125
181
18879
T63
H
R
L
R
G
S
L
T
A
I
K
T
R
A
P
Chicken
Gallus gallus
NP_001026197
166
17509
A53
H
R
L
R
G
S
L
A
A
V
K
A
R
A
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_938181
166
17419
T53
H
R
M
K
G
S
L
T
A
I
R
T
R
A
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VNA0
179
18651
A53
Y
R
L
S
G
G
L
A
A
V
R
A
R
S
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O44477
181
19078
R51
K
K
L
V
G
M
M
R
E
V
R
M
R
S
T
Sea Urchin
Strong. purpuratus
XP_783220
166
17560
L53
H
R
L
V
G
S
F
L
A
I
K
H
K
A
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SP35
243
25553
Q53
S
R
F
V
G
G
T
Q
S
V
S
M
N
A
P
Baker's Yeast
Sacchar. cerevisiae
P39515
158
16566
R46
R
N
S
P
L
G
E
R
G
S
G
A
M
S
A
Red Bread Mold
Neurospora crassa
P59670
155
16165
E43
F
R
N
S
P
Y
G
E
R
R
I
G
A
I
T
Conservation
Percent
Protein Identity:
100
97.6
99.4
99.4
N.A.
95.9
96.4
N.A.
90
91.8
N.A.
87.1
N.A.
50.8
N.A.
47.5
67.2
Protein Similarity:
100
98.2
99.4
99.4
N.A.
97.6
97.6
N.A.
91.7
94.7
N.A.
94.1
N.A.
67
N.A.
61.3
77.1
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
80
N.A.
80
N.A.
40
N.A.
20
66.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
86.6
N.A.
100
N.A.
66.6
N.A.
53.3
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
39
46.2
47.3
Protein Similarity:
N.A.
N.A.
N.A.
47.3
60.2
59
P-Site Identity:
N.A.
N.A.
N.A.
26.6
0
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
40
6.6
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
14
74
0
0
20
7
74
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
7
7
7
0
0
0
0
0
0
% E
% Phe:
7
0
7
0
0
0
7
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
87
20
7
0
7
0
7
7
0
0
7
% G
% His:
67
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
60
7
0
0
7
0
% I
% Lys:
7
7
0
7
0
0
0
0
0
0
60
0
7
0
0
% K
% Leu:
0
0
74
0
7
0
67
7
0
0
0
0
0
0
0
% L
% Met:
0
0
7
0
0
7
7
0
0
0
0
14
7
0
0
% M
% Asn:
0
7
7
0
0
0
0
0
0
0
0
0
7
0
0
% N
% Pro:
0
0
0
7
7
0
0
0
0
0
0
0
0
0
74
% P
% Gln:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% Q
% Arg:
7
87
0
54
0
0
0
14
7
7
20
0
74
0
0
% R
% Ser:
7
0
7
14
0
67
0
0
7
7
7
0
0
20
0
% S
% Thr:
0
0
0
0
0
0
7
54
0
0
0
54
0
0
14
% T
% Val:
0
0
0
20
0
0
0
0
0
27
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _