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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TSNAX All Species: 43.03
Human Site: S265 Identified Species: 72.82
UniProt: Q99598 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99598 NP_005990.1 290 33112 S265 Y A L K V R G S E I P K H M L
Chimpanzee Pan troglodytes XP_514271 297 33933 S272 Y A L K V R G S E I P K H M L
Rhesus Macaque Macaca mulatta XP_001104647 290 33111 S265 Y A L K V R G S E I P K H M L
Dog Lupus familis XP_536345 290 33022 S265 Y A L K V R G S E I P K H M L
Cat Felis silvestris
Mouse Mus musculus Q9QZE7 290 32908 S265 Y A L K V R G S E I P K H M L
Rat Rattus norvegicus Q9JHB5 290 32987 S265 Y A L K V R G S E I P K H M L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514013 291 32599 S266 Y A L K V R G S E I P K H M L
Chicken Gallus gallus P79769 229 25942 I205 L K Y D V K K I E E V V Y D L
Frog Xenopus laevis NP_001079762 297 33943 S273 Y A L K V R G S E I P K H M L
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres NP_001027792 280 31268 S255 Y T L R V R G S E I P K H M L
Fruit Fly Dros. melanogaster NP_732021 298 34272 L262 T T M K Q S V L K A E N V C Y
Honey Bee Apis mellifera XP_001121665 258 29943 E234 T I K I R G S E I P K H I L V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785495 341 39072 S312 Y V I K V R G S E I P K H M L
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001168132 259 28796 S235 F S V H V R G S E Y I P L L E
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.3 98.9 97.2 N.A. 90.6 90.3 N.A. 79.7 21.7 64.9 N.A. 59.3 36.2 38.6 N.A. 40.7
Protein Similarity: 100 97.6 99.6 98.9 N.A. 95.1 95.5 N.A. 87.9 37.2 81.8 N.A. 74.8 55.3 60.3 N.A. 60.4
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 100 20 100 N.A. 86.6 6.6 0 N.A. 86.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 33.3 100 N.A. 93.3 20 13.3 N.A. 93.3
Percent
Protein Identity: N.A. 32.4 N.A. N.A. N.A. N.A.
Protein Similarity: N.A. 50.6 N.A. N.A. N.A. N.A.
P-Site Identity: N.A. 33.3 N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. 60 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 58 0 0 0 0 0 0 0 8 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % C
% Asp: 0 0 0 8 0 0 0 0 0 0 0 0 0 8 0 % D
% Glu: 0 0 0 0 0 0 0 8 86 8 8 0 0 0 8 % E
% Phe: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 8 79 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 8 0 0 0 0 0 0 0 8 72 0 0 % H
% Ile: 0 8 8 8 0 0 0 8 8 72 8 0 8 0 0 % I
% Lys: 0 8 8 72 0 8 8 0 8 0 8 72 0 0 0 % K
% Leu: 8 0 65 0 0 0 0 8 0 0 0 0 8 15 79 % L
% Met: 0 0 8 0 0 0 0 0 0 0 0 0 0 72 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 8 72 8 0 0 0 % P
% Gln: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 8 8 79 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 8 0 0 0 8 8 79 0 0 0 0 0 0 0 % S
% Thr: 15 15 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 8 8 0 86 0 8 0 0 0 8 8 8 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 72 0 8 0 0 0 0 0 0 8 0 0 8 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _