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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TSNAX All Species: 22.73
Human Site: T245 Identified Species: 38.46
UniProt: Q99598 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99598 NP_005990.1 290 33112 T245 E V S K K L Y T L K Q S L A K
Chimpanzee Pan troglodytes XP_514271 297 33933 T252 E V S K K L Y T L K Q S L A K
Rhesus Macaque Macaca mulatta XP_001104647 290 33111 T245 E V S K K L Y T L K Q S L A K
Dog Lupus familis XP_536345 290 33022 T245 E V S K K L Y T L K Q S L A K
Cat Felis silvestris
Mouse Mus musculus Q9QZE7 290 32908 T245 E V S K K L Y T L K Q S L A K
Rat Rattus norvegicus Q9JHB5 290 32987 T245 E V S K K L Y T L K Q S L S K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514013 291 32599 V246 E V S K K L Y V L K Q S L G K
Chicken Gallus gallus P79769 229 25942 N185 D S G F R L L N L K N D S L R
Frog Xenopus laevis NP_001079762 297 33943 V253 E I S R K I H V L K Q S L S K
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres NP_001027792 280 31268 V235 E V S K K L H V L R Q S L G K
Fruit Fly Dros. melanogaster NP_732021 298 34272 L242 F Y S G Y I S L N C Q R A R E
Honey Bee Apis mellifera XP_001121665 258 29943 L214 I N R K L C T L K Q S L H K M
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785495 341 39072 V292 E M V R K S T V M R Q S L K K
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001168132 259 28796 V215 E M K K K M E V M L Q S V V K
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.3 98.9 97.2 N.A. 90.6 90.3 N.A. 79.7 21.7 64.9 N.A. 59.3 36.2 38.6 N.A. 40.7
Protein Similarity: 100 97.6 99.6 98.9 N.A. 95.1 95.5 N.A. 87.9 37.2 81.8 N.A. 74.8 55.3 60.3 N.A. 60.4
P-Site Identity: 100 100 100 100 N.A. 100 93.3 N.A. 86.6 20 60 N.A. 73.3 13.3 6.6 N.A. 40
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 86.6 40 93.3 N.A. 86.6 26.6 13.3 N.A. 66.6
Percent
Protein Identity: N.A. 32.4 N.A. N.A. N.A. N.A.
Protein Similarity: N.A. 50.6 N.A. N.A. N.A. N.A.
P-Site Identity: N.A. 40 N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. 66.6 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 8 36 0 % A
% Cys: 0 0 0 0 0 8 0 0 0 8 0 0 0 0 0 % C
% Asp: 8 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % D
% Glu: 79 0 0 0 0 0 8 0 0 0 0 0 0 0 8 % E
% Phe: 8 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 8 8 0 0 0 0 0 0 0 0 0 15 0 % G
% His: 0 0 0 0 0 0 15 0 0 0 0 0 8 0 0 % H
% Ile: 8 8 0 0 0 15 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 8 72 79 0 0 0 8 65 0 0 0 15 79 % K
% Leu: 0 0 0 0 8 65 8 15 72 8 0 8 72 8 0 % L
% Met: 0 15 0 0 0 8 0 0 15 0 0 0 0 0 8 % M
% Asn: 0 8 0 0 0 0 0 8 8 0 8 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 8 86 0 0 0 0 % Q
% Arg: 0 0 8 15 8 0 0 0 0 15 0 8 0 8 8 % R
% Ser: 0 8 72 0 0 8 8 0 0 0 8 79 8 15 0 % S
% Thr: 0 0 0 0 0 0 15 43 0 0 0 0 0 0 0 % T
% Val: 0 58 8 0 0 0 0 36 0 0 0 0 8 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 8 0 50 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _