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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ELF4 All Species: 14.85
Human Site: S648 Identified Species: 36.3
UniProt: Q99607 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99607 NP_001120669.1 663 70730 S648 S P T P A P F S P F N P T S L
Chimpanzee Pan troglodytes XP_001149288 619 67453 V606 S N G F T S Q V A M K Q N E L
Rhesus Macaque Macaca mulatta XP_001092376 671 71608 S656 S P T P A P F S P F N P T S L
Dog Lupus familis XP_549250 663 70717 S648 S P T P A P F S P F N P T S L
Cat Felis silvestris
Mouse Mus musculus Q9Z2U4 655 70695 F642 T Q A P F S P F N P T S L I K
Rat Rattus norvegicus XP_229125 660 71261 S645 S P T Q A P F S P F N P T S L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515225 550 59810 A537 G F Q S H V A A M K P E S E Q
Chicken Gallus gallus NP_001006269 625 68248 Q612 N S F P S N I Q A K Q E N E P
Frog Xenopus laevis NP_001088229 636 69895 E623 N G F P S P L E I K Q E N D L
Zebra Danio Brachydanio rerio NP_571234 435 48321 T422 L D S R L P T T G H T P H S A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 35.9 82.8 89.2 N.A. 78.5 78.8 N.A. 29.8 35.5 34.6 35.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 51.2 87 92.4 N.A. 85.9 86.5 N.A. 42.8 50.8 47.6 46.9 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 13.3 100 100 N.A. 6.6 93.3 N.A. 0 6.6 20 20 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 13.3 100 100 N.A. 13.3 93.3 N.A. 13.3 20 33.3 33.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 40 0 10 10 20 0 0 0 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 0 0 0 0 0 0 0 0 0 0 0 10 0 % D
% Glu: 0 0 0 0 0 0 0 10 0 0 0 30 0 30 0 % E
% Phe: 0 10 20 10 10 0 40 10 0 40 0 0 0 0 0 % F
% Gly: 10 10 10 0 0 0 0 0 10 0 0 0 0 0 0 % G
% His: 0 0 0 0 10 0 0 0 0 10 0 0 10 0 0 % H
% Ile: 0 0 0 0 0 0 10 0 10 0 0 0 0 10 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 30 10 0 0 0 10 % K
% Leu: 10 0 0 0 10 0 10 0 0 0 0 0 10 0 60 % L
% Met: 0 0 0 0 0 0 0 0 10 10 0 0 0 0 0 % M
% Asn: 20 10 0 0 0 10 0 0 10 0 40 0 30 0 0 % N
% Pro: 0 40 0 60 0 60 10 0 40 10 10 50 0 0 10 % P
% Gln: 0 10 10 10 0 0 10 10 0 0 20 10 0 0 10 % Q
% Arg: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 50 10 10 10 20 20 0 40 0 0 0 10 10 50 0 % S
% Thr: 10 0 40 0 10 0 10 10 0 0 20 0 40 0 0 % T
% Val: 0 0 0 0 0 10 0 10 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _