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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ELF4 All Species: 16.97
Human Site: T581 Identified Species: 41.48
UniProt: Q99607 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99607 NP_001120669.1 663 70730 T581 A H L Q P L P T Q V V S R G S
Chimpanzee Pan troglodytes XP_001149288 619 67453 P539 A P V V T F S P R S S Q L V A
Rhesus Macaque Macaca mulatta XP_001092376 671 71608 T589 A H L Q P L P T Q V V S R G S
Dog Lupus familis XP_549250 663 70717 T581 A H L Q P L P T Q V V S R G S
Cat Felis silvestris
Mouse Mus musculus Q9Z2U4 655 70695 L575 L L R D Q G H L Q P L P S Q V
Rat Rattus norvegicus XP_229125 660 71261 S578 A H L Q P L Q S Q A L S R G S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515225 550 59810 H470 G G S Q L V A H P P G T V I T
Chicken Gallus gallus NP_001006269 625 68248 S545 V T F S P S S S Q V V A H P S
Frog Xenopus laevis NP_001088229 636 69895 S556 M S F S T S S S P L L T Q P T
Zebra Danio Brachydanio rerio NP_571234 435 48321 A355 K T S R T A S A D G S C P P A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 35.9 82.8 89.2 N.A. 78.5 78.8 N.A. 29.8 35.5 34.6 35.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 51.2 87 92.4 N.A. 85.9 86.5 N.A. 42.8 50.8 47.6 46.9 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 6.6 100 100 N.A. 6.6 73.3 N.A. 6.6 33.3 0 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 26.6 100 100 N.A. 13.3 86.6 N.A. 26.6 46.6 40 13.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 50 0 0 0 0 10 10 10 0 10 0 10 0 0 20 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % C
% Asp: 0 0 0 10 0 0 0 0 10 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 20 0 0 10 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 10 0 0 0 10 0 0 0 10 10 0 0 40 0 % G
% His: 0 40 0 0 0 0 10 10 0 0 0 0 10 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % I
% Lys: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 10 10 40 0 10 40 0 10 0 10 30 0 10 0 0 % L
% Met: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 10 0 0 50 0 30 10 20 20 0 10 10 30 0 % P
% Gln: 0 0 0 50 10 0 10 0 60 0 0 10 10 10 0 % Q
% Arg: 0 0 10 10 0 0 0 0 10 0 0 0 40 0 0 % R
% Ser: 0 10 20 20 0 20 40 30 0 10 20 40 10 0 50 % S
% Thr: 0 20 0 0 30 0 0 30 0 0 0 20 0 0 20 % T
% Val: 10 0 10 10 0 10 0 0 0 40 40 0 10 10 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _