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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF3C
All Species:
21.82
Human Site:
S532
Identified Species:
36.92
UniProt:
Q99613
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99613
NP_001032897.1
913
105344
S532
P
P
E
G
S
S
K
S
E
Q
D
Q
A
E
N
Chimpanzee
Pan troglodytes
XP_510902
575
66735
T228
D
R
T
D
R
I
R
T
C
A
I
L
C
H
I
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536923
913
105495
S532
P
P
E
G
S
S
K
S
E
Q
D
Q
A
E
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8R1B4
911
105513
S530
P
P
E
G
S
S
K
S
E
Q
D
Q
A
E
N
Rat
Rattus norvegicus
B5DFC8
911
105416
S530
P
P
E
G
S
S
K
S
E
Q
D
Q
A
E
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q4QR58
926
106985
S534
S
T
E
Q
E
S
K
S
E
Q
D
Q
A
E
N
Zebra Danio
Brachydanio rerio
Q6PFQ2
926
106349
S531
G
L
Q
G
E
T
K
S
E
Q
D
Q
E
E
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
A1ZAX1
910
105636
K498
F
D
P
E
V
L
K
K
K
R
G
E
L
P
A
Honey Bee
Apis mellifera
XP_623580
889
103950
Q497
F
D
P
N
V
L
K
Q
K
E
G
E
L
G
P
Nematode Worm
Caenorhab. elegans
O02328
898
103824
A490
Y
M
M
R
I
E
H
A
Y
Y
K
Y
Q
D
Q
Sea Urchin
Strong. purpuratus
XP_787192
1170
135125
E706
E
V
K
L
E
E
G
E
E
E
K
E
K
G
K
Poplar Tree
Populus trichocarpa
XP_002323353
895
101455
S456
S
S
A
F
V
V
T
S
E
L
V
P
R
K
P
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O49160
900
102930
P463
P
T
S
F
I
V
V
P
E
V
V
P
R
K
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SBD4
872
98381
A472
W
K
Q
V
S
A
E
A
D
S
E
I
T
P
R
Conservation
Percent
Protein Identity:
100
62.4
N.A.
98.5
N.A.
96.7
96.1
N.A.
N.A.
N.A.
79.2
76.1
N.A.
53
55.8
44.4
43.9
Protein Similarity:
100
62.6
N.A.
99.4
N.A.
97.6
97.6
N.A.
N.A.
N.A.
89.5
86.2
N.A.
70
72.5
64.5
58.9
P-Site Identity:
100
0
N.A.
100
N.A.
100
100
N.A.
N.A.
N.A.
73.3
53.3
N.A.
6.6
6.6
0
6.6
P-Site Similarity:
100
13.3
N.A.
100
N.A.
100
100
N.A.
N.A.
N.A.
73.3
73.3
N.A.
26.6
26.6
13.3
26.6
Percent
Protein Identity:
37
N.A.
N.A.
35.1
N.A.
33.6
Protein Similarity:
55.2
N.A.
N.A.
53
N.A.
54
P-Site Identity:
13.3
N.A.
N.A.
13.3
N.A.
6.6
P-Site Similarity:
20
N.A.
N.A.
20
N.A.
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
8
0
15
0
8
0
0
36
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
8
0
0
% C
% Asp:
8
15
0
8
0
0
0
0
8
0
43
0
0
8
0
% D
% Glu:
8
0
36
8
22
15
8
8
65
15
8
22
8
43
0
% E
% Phe:
15
0
0
15
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
36
0
0
8
0
0
0
15
0
0
15
0
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
0
8
0
% H
% Ile:
0
0
0
0
15
8
0
0
0
0
8
8
0
0
8
% I
% Lys:
0
8
8
0
0
0
58
8
15
0
15
0
8
15
8
% K
% Leu:
0
8
0
8
0
15
0
0
0
8
0
8
15
0
0
% L
% Met:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
36
% N
% Pro:
36
29
15
0
0
0
0
8
0
0
0
15
0
15
22
% P
% Gln:
0
0
15
8
0
0
0
8
0
43
0
43
8
0
8
% Q
% Arg:
0
8
0
8
8
0
8
0
0
8
0
0
15
0
8
% R
% Ser:
15
8
8
0
36
36
0
50
0
8
0
0
0
0
8
% S
% Thr:
0
15
8
0
0
8
8
8
0
0
0
0
8
0
0
% T
% Val:
0
8
0
8
22
15
8
0
0
8
15
0
0
0
0
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
8
8
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _