KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF3C
All Species:
22.73
Human Site:
Y116
Identified Species:
38.46
UniProt:
Q99613
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99613
NP_001032897.1
913
105344
Y116
I
L
A
D
L
E
D
Y
L
N
E
L
W
E
D
Chimpanzee
Pan troglodytes
XP_510902
575
66735
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536923
913
105495
Y116
I
L
A
D
L
E
D
Y
L
N
E
L
W
E
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8R1B4
911
105513
Y116
I
L
A
D
L
E
D
Y
L
N
E
L
W
E
D
Rat
Rattus norvegicus
B5DFC8
911
105416
Y116
I
L
A
D
L
E
D
Y
L
N
E
L
W
E
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q4QR58
926
106985
Y116
L
L
S
D
L
D
D
Y
L
N
E
L
W
E
D
Zebra Danio
Brachydanio rerio
Q6PFQ2
926
106349
Y116
L
L
A
D
L
E
D
Y
L
N
Q
L
W
E
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
A1ZAX1
910
105636
D121
F
I
N
E
V
W
E
D
R
E
G
R
K
N
L
Honey Bee
Apis mellifera
XP_623580
889
103950
E116
E
M
E
D
F
I
N
E
V
W
E
D
R
E
G
Nematode Worm
Caenorhab. elegans
O02328
898
103824
E118
I
R
S
L
V
E
I
E
D
Y
V
N
K
L
W
Sea Urchin
Strong. purpuratus
XP_787192
1170
135125
F117
C
L
V
E
L
E
E
F
V
N
E
L
W
E
D
Poplar Tree
Populus trichocarpa
XP_002323353
895
101455
F127
A
L
V
M
L
E
D
F
L
N
Q
A
L
A
N
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O49160
900
102930
F119
T
L
V
M
L
E
D
F
L
N
E
A
L
A
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SBD4
872
98381
I116
Q
I
Q
N
G
Q
K
I
N
D
W
S
L
I
A
Conservation
Percent
Protein Identity:
100
62.4
N.A.
98.5
N.A.
96.7
96.1
N.A.
N.A.
N.A.
79.2
76.1
N.A.
53
55.8
44.4
43.9
Protein Similarity:
100
62.6
N.A.
99.4
N.A.
97.6
97.6
N.A.
N.A.
N.A.
89.5
86.2
N.A.
70
72.5
64.5
58.9
P-Site Identity:
100
0
N.A.
100
N.A.
100
100
N.A.
N.A.
N.A.
80
86.6
N.A.
0
20
13.3
60
P-Site Similarity:
100
0
N.A.
100
N.A.
100
100
N.A.
N.A.
N.A.
100
100
N.A.
26.6
40
26.6
86.6
Percent
Protein Identity:
37
N.A.
N.A.
35.1
N.A.
33.6
Protein Similarity:
55.2
N.A.
N.A.
53
N.A.
54
P-Site Identity:
40
N.A.
N.A.
46.6
N.A.
0
P-Site Similarity:
60
N.A.
N.A.
60
N.A.
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
36
0
0
0
0
0
0
0
0
15
0
15
8
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
50
0
8
58
8
8
8
0
8
0
0
50
% D
% Glu:
8
0
8
15
0
65
15
15
0
8
58
0
0
58
0
% E
% Phe:
8
0
0
0
8
0
0
22
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
8
0
0
0
0
0
8
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
36
15
0
0
0
8
8
8
0
0
0
0
0
8
0
% I
% Lys:
0
0
0
0
0
0
8
0
0
0
0
0
15
0
0
% K
% Leu:
15
65
0
8
65
0
0
0
58
0
0
50
22
8
8
% L
% Met:
0
8
0
15
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
8
0
0
8
0
8
65
0
8
0
8
15
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
0
8
0
0
8
0
0
0
0
15
0
0
0
0
% Q
% Arg:
0
8
0
0
0
0
0
0
8
0
0
8
8
0
0
% R
% Ser:
0
0
15
0
0
0
0
0
0
0
0
8
0
0
0
% S
% Thr:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
22
0
15
0
0
0
15
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
8
0
0
0
8
8
0
50
0
8
% W
% Tyr:
0
0
0
0
0
0
0
43
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _