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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF3C
All Species:
15.15
Human Site:
Y904
Identified Species:
25.64
UniProt:
Q99613
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.31
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99613
NP_001032897.1
913
105344
Y904
G
Y
M
R
R
G
G
Y
R
Q
Q
Q
S
Q
T
Chimpanzee
Pan troglodytes
XP_510902
575
66735
R567
Y
M
R
R
G
G
Y
R
Q
Q
Q
S
Q
T
A
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536923
913
105495
Y904
G
Y
M
R
R
G
G
Y
R
Q
Q
Q
S
Q
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8R1B4
911
105513
Y902
G
Y
M
R
R
G
G
Y
R
Q
Q
Q
S
Q
T
Rat
Rattus norvegicus
B5DFC8
911
105416
Y902
G
Y
M
R
R
G
G
Y
R
Q
Q
Q
S
Q
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q4QR58
926
106985
R906
D
Q
K
D
Q
Y
Q
R
K
E
G
G
Y
M
R
Zebra Danio
Brachydanio rerio
Q6PFQ2
926
106349
Q903
Q
G
Y
Q
R
G
D
Q
K
G
G
Y
Q
Q
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
A1ZAX1
910
105636
G870
R
N
Q
N
N
Q
G
G
N
W
L
G
Q
R
R
Honey Bee
Apis mellifera
XP_623580
889
103950
G869
N
R
Q
G
Q
D
W
G
R
Q
R
R
D
R
D
Nematode Worm
Caenorhab. elegans
O02328
898
103824
S861
Q
G
D
K
Q
K
G
S
G
G
Y
Q
G
E
R
Sea Urchin
Strong. purpuratus
XP_787192
1170
135125
R1077
G
G
Y
K
D
G
G
R
G
G
Y
R
G
G
G
Poplar Tree
Populus trichocarpa
XP_002323353
895
101455
K824
N
A
A
A
S
G
G
K
W
Q
E
K
S
S
F
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O49160
900
102930
G831
A
G
A
A
S
G
G
G
G
Y
W
Q
D
K
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SBD4
872
98381
G842
R
G
G
G
Q
R
G
G
R
G
G
A
R
T
G
Conservation
Percent
Protein Identity:
100
62.4
N.A.
98.5
N.A.
96.7
96.1
N.A.
N.A.
N.A.
79.2
76.1
N.A.
53
55.8
44.4
43.9
Protein Similarity:
100
62.6
N.A.
99.4
N.A.
97.6
97.6
N.A.
N.A.
N.A.
89.5
86.2
N.A.
70
72.5
64.5
58.9
P-Site Identity:
100
26.6
N.A.
100
N.A.
100
100
N.A.
N.A.
N.A.
0
20
N.A.
6.6
13.3
13.3
20
P-Site Similarity:
100
33.3
N.A.
100
N.A.
100
100
N.A.
N.A.
N.A.
20
33.3
N.A.
13.3
40
33.3
33.3
Percent
Protein Identity:
37
N.A.
N.A.
35.1
N.A.
33.6
Protein Similarity:
55.2
N.A.
N.A.
53
N.A.
54
P-Site Identity:
26.6
N.A.
N.A.
20
N.A.
13.3
P-Site Similarity:
40
N.A.
N.A.
26.6
N.A.
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
15
15
0
0
0
0
0
0
0
8
0
0
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
8
8
8
8
8
0
0
0
0
0
15
0
8
% D
% Glu:
0
0
0
0
0
0
0
0
0
8
8
0
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
36
36
8
15
8
65
72
29
22
29
22
15
15
8
15
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
8
15
0
8
0
8
15
0
0
8
0
8
8
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% L
% Met:
0
8
29
0
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
15
8
0
8
8
0
0
0
8
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
15
8
15
8
29
8
8
8
8
50
36
43
22
36
0
% Q
% Arg:
15
8
8
36
36
8
0
22
43
0
8
15
8
15
22
% R
% Ser:
0
0
0
0
15
0
0
8
0
0
0
8
36
8
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
15
29
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
8
0
8
8
8
0
0
0
0
% W
% Tyr:
8
29
15
0
0
8
8
29
0
8
15
8
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _