KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTC1
All Species:
34.24
Human Site:
S116
Identified Species:
53.81
UniProt:
Q99614
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99614
NP_003305.1
292
33526
S116
K
Q
K
R
R
E
E
S
T
R
L
K
E
E
G
Chimpanzee
Pan troglodytes
XP_001141156
292
33408
S116
K
Q
K
R
R
E
E
S
T
R
L
K
E
E
G
Rhesus Macaque
Macaca mulatta
XP_001083639
292
33646
S116
K
Q
K
R
R
E
E
S
T
R
L
K
E
E
G
Dog
Lupus familis
XP_546270
293
33698
S117
K
Q
K
R
R
E
E
S
T
R
L
K
E
E
G
Cat
Felis silvestris
Mouse
Mus musculus
Q91Z38
292
33244
S116
K
Q
K
R
R
E
E
S
A
K
L
K
E
E
G
Rat
Rattus norvegicus
NP_001005529
292
33291
S116
K
Q
K
R
R
E
E
S
A
K
L
K
E
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506286
295
33897
S118
K
Q
K
R
K
K
E
S
A
R
L
K
E
E
G
Chicken
Gallus gallus
XP_414484
343
39127
S167
K
Q
K
R
R
K
E
S
T
T
L
K
E
K
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001007383
319
36919
S142
R
E
S
R
R
K
E
S
L
E
L
K
E
K
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650543
263
29383
A113
K
N
D
D
A
E
G
A
A
K
T
Y
T
E
A
Honey Bee
Apis mellifera
XP_623446
277
32061
A104
K
E
S
L
K
A
E
A
E
K
Y
K
N
E
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782508
374
41657
A194
K
V
E
L
K
D
E
A
Q
S
H
K
A
K
G
Poplar Tree
Populus trichocarpa
XP_002324511
278
30733
A105
I
Q
R
G
I
E
E
A
N
E
A
K
L
E
G
Maize
Zea mays
NP_001136906
255
27711
E107
E
E
A
L
S
K
Y
E
M
A
L
Q
I
A
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_194777
277
30908
E107
K
A
L
A
E
A
N
E
A
K
A
E
G
N
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
97.5
87.7
N.A.
83.5
83.9
N.A.
72.5
59.1
N.A.
52.3
N.A.
42.8
44.5
N.A.
38.7
Protein Similarity:
100
99.6
98.6
93.1
N.A.
90.7
91.7
N.A.
84.4
72.5
N.A.
70.8
N.A.
60.9
64
N.A.
57.7
P-Site Identity:
100
100
100
100
N.A.
86.6
86.6
N.A.
80
80
N.A.
53.3
N.A.
20
33.3
N.A.
26.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
93.3
93.3
N.A.
80
N.A.
33.3
60
N.A.
60
Percent
Protein Identity:
35.2
32.5
N.A.
34.2
N.A.
N.A.
Protein Similarity:
50.6
50.6
N.A.
55.1
N.A.
N.A.
P-Site Identity:
40
6.6
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
53.3
33.3
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
7
7
7
14
0
27
34
7
14
0
7
7
14
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
7
7
0
7
0
0
0
0
0
0
0
0
0
% D
% Glu:
7
20
7
0
7
54
80
14
7
14
0
7
60
67
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
7
0
0
7
0
0
0
0
0
7
0
80
% G
% His:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% H
% Ile:
7
0
0
0
7
0
0
0
0
0
0
0
7
0
0
% I
% Lys:
80
0
54
0
20
27
0
0
0
34
0
80
0
20
7
% K
% Leu:
0
0
7
20
0
0
0
0
7
0
67
0
7
0
0
% L
% Met:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% M
% Asn:
0
7
0
0
0
0
7
0
7
0
0
0
7
7
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
60
0
0
0
0
0
0
7
0
0
7
0
0
0
% Q
% Arg:
7
0
7
60
54
0
0
0
0
34
0
0
0
0
0
% R
% Ser:
0
0
14
0
7
0
0
60
0
7
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
34
7
7
0
7
0
0
% T
% Val:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
7
0
0
0
7
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _