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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTC1
All Species:
25.76
Human Site:
S90
Identified Species:
40.48
UniProt:
Q99614
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99614
NP_003305.1
292
33526
S90
S
N
E
D
V
N
S
S
E
L
D
E
E
Y
L
Chimpanzee
Pan troglodytes
XP_001141156
292
33408
S90
S
N
E
D
V
N
S
S
E
L
D
E
G
Y
L
Rhesus Macaque
Macaca mulatta
XP_001083639
292
33646
S90
S
N
E
D
V
N
S
S
E
L
D
E
E
Y
L
Dog
Lupus familis
XP_546270
293
33698
S91
P
D
D
N
V
N
S
S
E
L
D
E
E
Y
L
Cat
Felis silvestris
Mouse
Mus musculus
Q91Z38
292
33244
S90
K
A
S
D
D
S
S
S
E
L
D
E
E
Y
L
Rat
Rattus norvegicus
NP_001005529
292
33291
S90
K
A
S
D
E
S
S
S
E
L
E
E
E
Y
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506286
295
33897
P92
L
D
D
N
V
T
P
P
E
P
D
E
E
S
L
Chicken
Gallus gallus
XP_414484
343
39127
T141
E
N
S
T
R
K
Q
T
E
L
D
E
E
Y
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001007383
319
36919
A116
K
E
E
T
V
K
V
A
E
Y
D
D
E
Y
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650543
263
29383
L87
K
D
L
S
P
E
Q
L
T
A
N
K
E
K
A
Honey Bee
Apis mellifera
XP_623446
277
32061
D78
G
D
A
N
H
E
K
D
N
M
D
E
E
I
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782508
374
41657
E168
G
L
K
A
E
E
D
E
D
D
G
L
H
E
E
Poplar Tree
Populus trichocarpa
XP_002324511
278
30733
S79
N
V
S
K
E
I
S
S
K
N
T
T
E
D
Q
Maize
Zea mays
NP_001136906
255
27711
S81
Q
L
R
E
K
S
R
S
Q
A
N
D
A
K
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_194777
277
30908
Q81
H
S
E
K
K
E
E
Q
I
E
L
M
S
E
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
97.5
87.7
N.A.
83.5
83.9
N.A.
72.5
59.1
N.A.
52.3
N.A.
42.8
44.5
N.A.
38.7
Protein Similarity:
100
99.6
98.6
93.1
N.A.
90.7
91.7
N.A.
84.4
72.5
N.A.
70.8
N.A.
60.9
64
N.A.
57.7
P-Site Identity:
100
93.3
100
73.3
N.A.
66.6
60
N.A.
40
53.3
N.A.
46.6
N.A.
6.6
26.6
N.A.
0
P-Site Similarity:
100
93.3
100
93.3
N.A.
73.3
73.3
N.A.
60
60
N.A.
60
N.A.
26.6
46.6
N.A.
13.3
Percent
Protein Identity:
35.2
32.5
N.A.
34.2
N.A.
N.A.
Protein Similarity:
50.6
50.6
N.A.
55.1
N.A.
N.A.
P-Site Identity:
20
6.6
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
33.3
40
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
14
7
7
0
0
0
7
0
14
0
0
7
0
14
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
27
14
34
7
0
7
7
7
7
60
14
0
7
0
% D
% Glu:
7
7
34
7
20
27
7
7
60
7
7
60
74
14
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
14
0
0
0
0
0
0
0
0
0
7
0
7
0
7
% G
% His:
7
0
0
0
7
0
0
0
0
0
0
0
7
0
0
% H
% Ile:
0
0
0
0
0
7
0
0
7
0
0
0
0
7
0
% I
% Lys:
27
0
7
14
14
14
7
0
7
0
0
7
0
14
0
% K
% Leu:
7
14
7
0
0
0
0
7
0
47
7
7
0
0
67
% L
% Met:
0
0
0
0
0
0
0
0
0
7
0
7
0
0
0
% M
% Asn:
7
27
0
20
0
27
0
0
7
7
14
0
0
0
0
% N
% Pro:
7
0
0
0
7
0
7
7
0
7
0
0
0
0
0
% P
% Gln:
7
0
0
0
0
0
14
7
7
0
0
0
0
0
7
% Q
% Arg:
0
0
7
0
7
0
7
0
0
0
0
0
0
0
0
% R
% Ser:
20
7
27
7
0
20
47
54
0
0
0
0
7
7
0
% S
% Thr:
0
0
0
14
0
7
0
7
7
0
7
7
0
0
0
% T
% Val:
0
7
0
0
40
0
7
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
7
0
0
0
54
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _