KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTC1
All Species:
17.88
Human Site:
T23
Identified Species:
28.1
UniProt:
Q99614
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99614
NP_003305.1
292
33526
T23
N
G
L
K
V
T
D
T
Q
E
A
E
C
A
G
Chimpanzee
Pan troglodytes
XP_001141156
292
33408
T23
N
G
L
K
V
T
D
T
Q
E
A
E
C
A
G
Rhesus Macaque
Macaca mulatta
XP_001083639
292
33646
T23
N
G
L
K
V
T
D
T
Q
E
A
E
C
A
G
Dog
Lupus familis
XP_546270
293
33698
H23
N
G
L
K
V
T
D
H
Q
E
A
E
C
A
S
Cat
Felis silvestris
Mouse
Mus musculus
Q91Z38
292
33244
P23
N
G
L
K
V
A
D
P
Q
E
G
E
S
A
S
Rat
Rattus norvegicus
NP_001005529
292
33291
S23
N
G
L
K
V
T
D
S
Q
E
T
E
S
A
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506286
295
33897
A23
N
G
L
K
I
A
D
A
Q
R
A
G
S
S
C
Chicken
Gallus gallus
XP_414484
343
39127
Q69
D
H
L
K
L
S
D
Q
K
S
T
E
S
T
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001007383
319
36919
V35
G
E
V
R
H
S
D
V
I
M
A
Q
N
D
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650543
263
29383
T27
T
E
K
E
A
T
S
T
R
Q
S
E
K
D
V
Honey Bee
Apis mellifera
XP_623446
277
32061
L22
I
E
E
L
T
K
D
L
E
S
S
C
I
K
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782508
374
41657
S33
N
D
E
S
T
G
D
S
K
E
N
K
T
P
L
Poplar Tree
Populus trichocarpa
XP_002324511
278
30733
P22
P
K
P
P
Q
P
A
P
S
T
S
K
T
T
T
Maize
Zea mays
NP_001136906
255
27711
A26
S
E
E
K
A
A
A
A
A
G
G
E
A
A
R
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_194777
277
30908
S24
N
E
P
K
P
A
S
S
S
S
P
Q
P
T
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
97.5
87.7
N.A.
83.5
83.9
N.A.
72.5
59.1
N.A.
52.3
N.A.
42.8
44.5
N.A.
38.7
Protein Similarity:
100
99.6
98.6
93.1
N.A.
90.7
91.7
N.A.
84.4
72.5
N.A.
70.8
N.A.
60.9
64
N.A.
57.7
P-Site Identity:
100
100
100
86.6
N.A.
66.6
73.3
N.A.
46.6
26.6
N.A.
13.3
N.A.
20
6.6
N.A.
20
P-Site Similarity:
100
100
100
86.6
N.A.
66.6
80
N.A.
60
53.3
N.A.
40
N.A.
46.6
20
N.A.
40
Percent
Protein Identity:
35.2
32.5
N.A.
34.2
N.A.
N.A.
Protein Similarity:
50.6
50.6
N.A.
55.1
N.A.
N.A.
P-Site Identity:
0
20
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
13.3
26.6
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
14
27
14
14
7
0
40
0
7
47
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
7
27
0
7
% C
% Asp:
7
7
0
0
0
0
74
0
0
0
0
0
0
14
0
% D
% Glu:
0
34
20
7
0
0
0
0
7
47
0
60
0
0
14
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
7
47
0
0
0
7
0
0
0
7
14
7
0
0
20
% G
% His:
0
7
0
0
7
0
0
7
0
0
0
0
0
0
0
% H
% Ile:
7
0
0
0
7
0
0
0
7
0
0
0
7
0
0
% I
% Lys:
0
7
7
67
0
7
0
0
14
0
0
14
7
7
0
% K
% Leu:
0
0
54
7
7
0
0
7
0
0
0
0
0
0
7
% L
% Met:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% M
% Asn:
60
0
0
0
0
0
0
0
0
0
7
0
7
0
0
% N
% Pro:
7
0
14
7
7
7
0
14
0
0
7
0
7
7
0
% P
% Gln:
0
0
0
0
7
0
0
7
47
7
0
14
0
0
0
% Q
% Arg:
0
0
0
7
0
0
0
0
7
7
0
0
0
0
14
% R
% Ser:
7
0
0
7
0
14
14
20
14
20
20
0
27
7
27
% S
% Thr:
7
0
0
0
14
40
0
27
0
7
14
0
14
20
7
% T
% Val:
0
0
7
0
40
0
0
7
0
0
0
0
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _