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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTC1
All Species:
53.94
Human Site:
Y188
Identified Species:
84.76
UniProt:
Q99614
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99614
NP_003305.1
292
33526
Y188
A
I
Q
L
N
P
S
Y
I
R
A
I
L
R
R
Chimpanzee
Pan troglodytes
XP_001141156
292
33408
Y188
A
I
Q
L
N
P
S
Y
I
R
A
I
L
R
R
Rhesus Macaque
Macaca mulatta
XP_001083639
292
33646
Y188
A
I
Q
L
N
P
S
Y
I
R
A
I
L
R
R
Dog
Lupus familis
XP_546270
293
33698
Y189
A
I
Q
L
N
P
N
Y
I
R
A
I
L
R
R
Cat
Felis silvestris
Mouse
Mus musculus
Q91Z38
292
33244
Y188
A
I
Q
L
N
P
T
Y
I
R
A
I
L
R
R
Rat
Rattus norvegicus
NP_001005529
292
33291
Y188
A
I
Q
L
N
P
T
Y
I
R
A
I
L
R
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506286
295
33897
Y190
A
I
E
L
N
P
N
Y
I
R
A
I
L
R
R
Chicken
Gallus gallus
XP_414484
343
39127
Y239
A
V
E
L
D
P
N
Y
I
R
A
L
L
R
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001007383
319
36919
Y214
A
I
E
L
N
P
N
Y
V
R
A
I
L
R
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650543
263
29383
E180
R
A
K
L
Y
E
Q
E
D
K
P
D
E
A
L
Honey Bee
Apis mellifera
XP_623446
277
32061
Y176
A
I
E
L
N
P
S
Y
V
K
V
Y
A
R
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782508
374
41657
Y266
A
L
E
L
H
P
H
Y
M
K
V
W
L
R
R
Poplar Tree
Populus trichocarpa
XP_002324511
278
30733
Y180
A
L
E
L
N
P
S
Y
M
K
A
L
V
R
R
Maize
Zea mays
NP_001136906
255
27711
Y174
A
H
E
K
L
E
H
Y
D
E
A
I
A
D
M
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_194777
277
30908
Y179
A
L
E
L
N
P
T
Y
N
K
A
L
V
R
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
97.5
87.7
N.A.
83.5
83.9
N.A.
72.5
59.1
N.A.
52.3
N.A.
42.8
44.5
N.A.
38.7
Protein Similarity:
100
99.6
98.6
93.1
N.A.
90.7
91.7
N.A.
84.4
72.5
N.A.
70.8
N.A.
60.9
64
N.A.
57.7
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
86.6
66.6
N.A.
80
N.A.
6.6
60
N.A.
46.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
N.A.
100
N.A.
20
80
N.A.
80
Percent
Protein Identity:
35.2
32.5
N.A.
34.2
N.A.
N.A.
Protein Similarity:
50.6
50.6
N.A.
55.1
N.A.
N.A.
P-Site Identity:
60
26.6
N.A.
53.3
N.A.
N.A.
P-Site Similarity:
100
33.3
N.A.
93.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
94
7
0
0
0
0
0
0
0
0
80
0
14
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
7
0
0
0
14
0
0
7
0
7
0
% D
% Glu:
0
0
54
0
0
14
0
7
0
7
0
0
7
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
7
0
0
7
0
14
0
0
0
0
0
0
0
0
% H
% Ile:
0
60
0
0
0
0
0
0
54
0
0
60
0
0
0
% I
% Lys:
0
0
7
7
0
0
0
0
0
34
0
0
0
0
0
% K
% Leu:
0
20
0
94
7
0
0
0
0
0
0
20
67
0
7
% L
% Met:
0
0
0
0
0
0
0
0
14
0
0
0
0
0
7
% M
% Asn:
0
0
0
0
74
0
27
0
7
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
87
0
0
0
0
7
0
0
0
0
% P
% Gln:
0
0
40
0
0
0
7
0
0
0
0
0
0
0
0
% Q
% Arg:
7
0
0
0
0
0
0
0
0
60
0
0
0
87
87
% R
% Ser:
0
0
0
0
0
0
34
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
20
0
0
0
0
0
0
0
0
% T
% Val:
0
7
0
0
0
0
0
0
14
0
14
0
14
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% W
% Tyr:
0
0
0
0
7
0
0
94
0
0
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _