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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TTC1 All Species: 39.7
Human Site: Y212 Identified Species: 62.38
UniProt: Q99614 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99614 NP_003305.1 292 33526 Y212 L D E A L E D Y K S I L E K D
Chimpanzee Pan troglodytes XP_001141156 292 33408 Y212 L D E A L E D Y K S I L E K D
Rhesus Macaque Macaca mulatta XP_001083639 292 33646 Y212 L D E A L E D Y K S I L E K D
Dog Lupus familis XP_546270 293 33698 Y213 L D E A L E D Y K S I L E K D
Cat Felis silvestris
Mouse Mus musculus Q91Z38 292 33244 Y212 L D E A L E D Y K S V L E K D
Rat Rattus norvegicus NP_001005529 292 33291 Y212 L D E A L E D Y K S I L E T D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506286 295 33897 Y214 L D E A L E D Y K S I L E K D
Chicken Gallus gallus XP_414484 343 39127 Y263 L D E A L E D Y K A I L E K D
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001007383 319 36919 Y238 L D E A L E D Y K T V L E K D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650543 263 29383 R204 D P G Q Q E A R E A Q I R L P
Honey Bee Apis mellifera XP_623446 277 32061 Y200 L D E A L E D Y K K I L T F D
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782508 374 41657 F290 L D E A L A D F K Q V L E L D
Poplar Tree Populus trichocarpa XP_002324511 278 30733 M204 F E E A I A D M K K I L E L D
Maize Zea mays NP_001136906 255 27711 L198 N Q Q A T R S L F R L E P L A
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_194777 277 30908 L203 F E D A V T D L K K I L E L D
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 97.5 87.7 N.A. 83.5 83.9 N.A. 72.5 59.1 N.A. 52.3 N.A. 42.8 44.5 N.A. 38.7
Protein Similarity: 100 99.6 98.6 93.1 N.A. 90.7 91.7 N.A. 84.4 72.5 N.A. 70.8 N.A. 60.9 64 N.A. 57.7
P-Site Identity: 100 100 100 100 N.A. 93.3 93.3 N.A. 100 93.3 N.A. 86.6 N.A. 6.6 80 N.A. 66.6
P-Site Similarity: 100 100 100 100 N.A. 100 93.3 N.A. 100 100 N.A. 100 N.A. 26.6 80 N.A. 80
Percent
Protein Identity: 35.2 32.5 N.A. 34.2 N.A. N.A.
Protein Similarity: 50.6 50.6 N.A. 55.1 N.A. N.A.
P-Site Identity: 53.3 6.6 N.A. 46.6 N.A. N.A.
P-Site Similarity: 66.6 20 N.A. 66.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 94 0 14 7 0 0 14 0 0 0 0 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 74 7 0 0 0 87 0 0 0 0 0 0 0 87 % D
% Glu: 0 14 80 0 0 74 0 0 7 0 0 7 80 0 0 % E
% Phe: 14 0 0 0 0 0 0 7 7 0 0 0 0 7 0 % F
% Gly: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 7 0 0 0 0 0 67 7 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 87 20 0 0 0 54 0 % K
% Leu: 74 0 0 0 74 0 0 14 0 0 7 87 0 34 0 % L
% Met: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % M
% Asn: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 7 0 0 0 0 0 0 0 0 0 0 7 0 7 % P
% Gln: 0 7 7 7 7 0 0 0 0 7 7 0 0 0 0 % Q
% Arg: 0 0 0 0 0 7 0 7 0 7 0 0 7 0 0 % R
% Ser: 0 0 0 0 0 0 7 0 0 47 0 0 0 0 0 % S
% Thr: 0 0 0 0 7 7 0 0 0 7 0 0 7 7 0 % T
% Val: 0 0 0 0 7 0 0 0 0 0 20 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 67 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _