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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: C12orf57 All Species: 18.18
Human Site: S97 Identified Species: 50
UniProt: Q99622 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0.5
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99622 NP_612434.1 126 13178 S97 A Q D P E I A S L S G K L K A
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001111088 126 13130 S97 A Q D P E I A S L S G K L K A
Dog Lupus familis XP_853381 126 13125 S97 A Q D P E I A S L S G K L K A
Cat Felis silvestris
Mouse Mus musculus O35127 126 13176 S97 A Q D P E I A S L S G K L K A
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001234404 210 21803 S182 S Q D P E I A S M S G K L K A
Frog Xenopus laevis Q6AX50 128 13579 E99 S Y E S Q D P E I A A M S S K
Zebra Danio Brachydanio rerio Q6TH01 122 13138 E94 M Y E T Q D P E I A A M S V K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001120666 119 13395 E90 T L E R E D P E V A Q L H S Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001182676 116 12673 E88 S A D N E V A E M A S R L K S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 98.4 96.8 N.A. 97.6 N.A. N.A. N.A. 52.3 59.3 70.6 N.A. N.A. 38 N.A. 41.2
Protein Similarity: 100 N.A. 100 97.6 N.A. 98.4 N.A. N.A. N.A. 55.7 75 81.7 N.A. N.A. 61.1 N.A. 59.5
P-Site Identity: 100 N.A. 100 100 N.A. 100 N.A. N.A. N.A. 86.6 0 0 N.A. N.A. 6.6 N.A. 33.3
P-Site Similarity: 100 N.A. 100 100 N.A. 100 N.A. N.A. N.A. 100 33.3 26.6 N.A. N.A. 26.6 N.A. 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 45 12 0 0 0 0 67 0 0 45 23 0 0 0 56 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 67 0 0 34 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 34 0 78 0 0 45 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 56 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 12 0 0 % H
% Ile: 0 0 0 0 0 56 0 0 23 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 56 0 67 23 % K
% Leu: 0 12 0 0 0 0 0 0 45 0 0 12 67 0 0 % L
% Met: 12 0 0 0 0 0 0 0 23 0 0 23 0 0 0 % M
% Asn: 0 0 0 12 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 56 0 0 34 0 0 0 0 0 0 0 0 % P
% Gln: 0 56 0 0 23 0 0 0 0 0 12 0 0 0 12 % Q
% Arg: 0 0 0 12 0 0 0 0 0 0 0 12 0 0 0 % R
% Ser: 34 0 0 12 0 0 0 56 0 56 12 0 23 23 12 % S
% Thr: 12 0 0 12 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 12 0 0 12 0 0 0 0 12 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 23 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _