KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PHB2
All Species:
22.73
Human Site:
S176
Identified Species:
45.45
UniProt:
Q99623
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99623
NP_001138303.1
299
33296
S176
T
E
R
A
K
D
F
S
L
I
L
D
D
V
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001111919
295
32862
S176
T
E
R
A
K
D
F
S
L
I
L
D
D
V
A
Dog
Lupus familis
XP_543843
283
31770
S176
T
E
R
A
K
D
F
S
L
I
L
D
D
V
A
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Q5XIH7
299
33294
S176
T
E
R
A
K
D
F
S
L
I
L
D
D
V
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZMN3
301
33318
S176
T
E
R
A
K
D
F
S
L
I
L
D
D
V
A
Frog
Xenopus laevis
NP_001086635
301
33336
S176
T
E
R
A
K
D
F
S
I
I
V
D
D
V
A
Zebra Danio
Brachydanio rerio
XP_002662479
303
33767
N184
F
E
R
A
K
D
F
N
I
I
L
D
D
V
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P24156
276
30365
G162
T
V
R
A
K
Q
F
G
F
I
L
D
D
I
S
Honey Bee
Apis mellifera
XP_624330
377
42191
N169
T
E
R
A
R
D
F
N
I
V
L
D
D
V
S
Nematode Worm
Caenorhab. elegans
P50093
294
32649
N175
I
E
R
A
L
D
F
N
I
I
L
D
D
V
S
Sea Urchin
Strong. purpuratus
XP_781225
294
32225
G175
T
D
R
A
S
D
F
G
L
I
L
D
D
V
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P50085
310
34388
N193
V
R
R
A
S
K
F
N
I
L
L
D
D
V
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.6
80.5
N.A.
N.A.
99.6
N.A.
N.A.
94.6
88
80.5
N.A.
47.1
55.9
62.2
69.2
Protein Similarity:
100
N.A.
98.6
84.9
N.A.
N.A.
100
N.A.
N.A.
97.3
96.3
90
N.A.
67.2
67.9
77.9
84.2
P-Site Identity:
100
N.A.
100
100
N.A.
N.A.
100
N.A.
N.A.
100
86.6
80
N.A.
60
66.6
66.6
73.3
P-Site Similarity:
100
N.A.
100
100
N.A.
N.A.
100
N.A.
N.A.
100
100
93.3
N.A.
73.3
100
86.6
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
50.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
70.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
100
0
0
0
0
0
0
0
0
0
0
59
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
0
0
84
0
0
0
0
0
100
100
0
0
% D
% Glu:
0
75
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
9
0
0
0
0
0
100
0
9
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
17
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
9
0
0
0
0
0
0
0
42
84
0
0
0
9
0
% I
% Lys:
0
0
0
0
67
9
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
9
0
0
0
50
9
92
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
34
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
9
100
0
9
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
17
0
0
50
0
0
0
0
0
0
42
% S
% Thr:
75
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
9
9
0
0
0
0
0
0
0
9
9
0
0
92
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _