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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PHB2 All Species: 13.94
Human Site: Y272 Identified Species: 27.88
UniProt: Q99623 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99623 NP_001138303.1 299 33296 Y272 A T S Q N R I Y L T A D N L V
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001111919 295 32862 K250 S K N P G Y I K L R K I R A A
Dog Lupus familis XP_543843 283 31770 P255 A P G A L A S P F S L L G R L
Cat Felis silvestris
Mouse Mus musculus
Rat Rattus norvegicus Q5XIH7 299 33294 Y272 A T S Q N R I Y L T A D N L V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZMN3 301 33318 Y272 A G S Q N R V Y L T A D N L V
Frog Xenopus laevis NP_001086635 301 33336 Y272 A S S Q N R V Y L N A D N L V
Zebra Danio Brachydanio rerio XP_002662479 303 33767 T271 A A Q N I A K T V A A S Q N K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P24156 276 30365 G229 G L L A K S F G E A G D G L V
Honey Bee Apis mellifera XP_624330 377 42191 L265 I A K K N L Y L F G N G L M L
Nematode Worm Caenorhab. elegans P50093 294 32649 A256 K L R K I R A A Q K I A R I V
Sea Urchin Strong. purpuratus XP_781225 294 32225 A240 S A V M L G E A I S S N P G Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P50085 310 34388 E267 K K S R D Y V E L K R L D T A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 98.6 80.5 N.A. N.A. 99.6 N.A. N.A. 94.6 88 80.5 N.A. 47.1 55.9 62.2 69.2
Protein Similarity: 100 N.A. 98.6 84.9 N.A. N.A. 100 N.A. N.A. 97.3 96.3 90 N.A. 67.2 67.9 77.9 84.2
P-Site Identity: 100 N.A. 13.3 6.6 N.A. N.A. 100 N.A. N.A. 86.6 80 13.3 N.A. 20 6.6 13.3 0
P-Site Similarity: 100 N.A. 26.6 20 N.A. N.A. 100 N.A. N.A. 93.3 93.3 20 N.A. 20 26.6 26.6 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 50.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 70.3 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 50 25 0 17 0 17 9 17 0 17 42 9 0 9 17 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 9 0 0 0 0 0 0 42 9 0 0 % D
% Glu: 0 0 0 0 0 0 9 9 9 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 9 0 17 0 0 0 0 0 0 % F
% Gly: 9 9 9 0 9 9 0 9 0 9 9 9 17 9 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 9 0 0 0 17 0 25 0 9 0 9 9 0 9 0 % I
% Lys: 17 17 9 17 9 0 9 9 0 17 9 0 0 0 9 % K
% Leu: 0 17 9 0 17 9 0 9 50 0 9 17 9 42 17 % L
% Met: 0 0 0 9 0 0 0 0 0 0 0 0 0 9 0 % M
% Asn: 0 0 9 9 42 0 0 0 0 9 9 9 34 9 0 % N
% Pro: 0 9 0 9 0 0 0 9 0 0 0 0 9 0 0 % P
% Gln: 0 0 9 34 0 0 0 0 9 0 0 0 9 0 0 % Q
% Arg: 0 0 9 9 0 42 0 0 0 9 9 0 17 9 0 % R
% Ser: 17 9 42 0 0 9 9 0 0 17 9 9 0 0 0 % S
% Thr: 0 17 0 0 0 0 0 9 0 25 0 0 0 9 0 % T
% Val: 0 0 9 0 0 0 25 0 9 0 0 0 0 0 50 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 17 9 34 0 0 0 0 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _