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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COPS8
All Species:
33.64
Human Site:
S183
Identified Species:
49.33
UniProt:
Q99627
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99627
NP_006701.1
209
23226
S183
F
N
K
F
I
P
L
S
E
P
A
P
V
P
P
Chimpanzee
Pan troglodytes
XP_001135161
209
23311
S183
F
N
K
F
I
P
L
S
E
P
A
P
L
P
P
Rhesus Macaque
Macaca mulatta
XP_001090380
647
71562
S621
F
N
K
F
I
P
L
S
E
P
A
P
V
P
P
Dog
Lupus familis
XP_534612
209
23195
S183
F
N
R
F
I
P
L
S
E
P
A
P
V
P
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8VBV7
209
23237
S183
L
N
R
F
I
P
L
S
E
P
A
P
V
P
P
Rat
Rattus norvegicus
Q6P4Z9
209
23217
S183
L
N
R
F
I
P
L
S
E
P
A
P
V
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507694
204
22617
S178
F
N
R
F
I
P
L
S
E
P
A
P
V
P
P
Chicken
Gallus gallus
NP_001041472
207
22961
S181
F
N
R
F
I
P
S
S
E
P
A
P
V
P
P
Frog
Xenopus laevis
Q6GQA6
195
21737
S171
V
M
P
K
K
P
D
S
A
P
L
S
L
I
P
Zebra Danio
Brachydanio rerio
Q7ZUZ0
191
21527
P167
I
M
P
Q
K
P
D
P
P
P
V
S
L
V
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KTH8
182
21413
A160
L
K
P
K
V
Q
E
A
P
P
A
R
G
N
D
Honey Bee
Apis mellifera
XP_391971
187
21201
S162
C
K
I
Q
K
E
E
S
N
L
V
N
E
V
C
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203845
168
18975
R146
P
K
K
P
V
P
S
R
E
A
P
A
P
S
E
Poplar Tree
Populus trichocarpa
XP_002298193
199
22672
V176
L
I
V
K
K
Q
S
V
K
T
E
Q
K
L
D
Maize
Zea mays
NP_001141592
196
22092
S173
L
T
V
K
K
P
K
S
Q
T
N
Q
K
L
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P43255
197
22528
V174
A
S
V
K
K
Q
A
V
K
R
E
Q
K
V
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.7
31.6
98
N.A.
95.2
95.6
N.A.
84.2
88
74.1
67.9
N.A.
27.2
46.8
N.A.
43.5
Protein Similarity:
100
96.6
32.2
99.5
N.A.
98
98
N.A.
91.8
93.7
85.1
77.9
N.A.
46.8
63.1
N.A.
63.1
P-Site Identity:
100
93.3
100
93.3
N.A.
86.6
86.6
N.A.
93.3
86.6
26.6
20
N.A.
13.3
6.6
N.A.
20
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
100
93.3
33.3
26.6
N.A.
26.6
6.6
N.A.
26.6
Percent
Protein Identity:
32.5
32.5
N.A.
33.4
N.A.
N.A.
Protein Similarity:
55.5
52.1
N.A.
53.1
N.A.
N.A.
P-Site Identity:
0
13.3
N.A.
0
N.A.
N.A.
P-Site Similarity:
6.6
20
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
0
0
7
7
7
7
57
7
0
0
0
% A
% Cys:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% C
% Asp:
0
0
0
0
0
0
13
0
0
0
0
0
0
0
25
% D
% Glu:
0
0
0
0
0
7
13
0
57
0
13
0
7
0
7
% E
% Phe:
38
0
0
50
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
7
7
7
0
50
0
0
0
0
0
0
0
0
7
0
% I
% Lys:
0
19
25
32
38
0
7
0
13
0
0
0
19
0
0
% K
% Leu:
32
0
0
0
0
0
44
0
0
7
7
0
19
13
0
% L
% Met:
0
13
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
50
0
0
0
0
0
0
7
0
7
7
0
7
0
% N
% Pro:
7
0
19
7
0
75
0
7
13
69
7
50
7
50
63
% P
% Gln:
0
0
0
13
0
19
0
0
7
0
0
19
0
0
0
% Q
% Arg:
0
0
32
0
0
0
0
7
0
7
0
7
0
0
0
% R
% Ser:
0
7
0
0
0
0
19
69
0
0
0
13
0
7
0
% S
% Thr:
0
7
0
0
0
0
0
0
0
13
0
0
0
0
0
% T
% Val:
7
0
19
0
13
0
0
13
0
0
13
0
44
19
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _