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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COPS8
All Species:
31.21
Human Site:
T101
Identified Species:
45.78
UniProt:
Q99627
Number Species:
15
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99627
NP_006701.1
209
23226
T101
N
A
H
Q
W
S
E
T
V
Q
P
I
M
E
A
Chimpanzee
Pan troglodytes
XP_001135161
209
23311
T101
N
A
H
Q
W
S
E
T
V
Q
P
I
M
E
A
Rhesus Macaque
Macaca mulatta
XP_001090380
647
71562
T539
N
A
H
Q
W
S
E
T
V
Q
P
I
M
E
A
Dog
Lupus familis
XP_534612
209
23195
T101
N
A
H
Q
W
S
E
T
V
Q
P
I
M
E
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8VBV7
209
23237
T101
N
A
H
Q
W
S
E
T
V
Q
P
I
M
E
A
Rat
Rattus norvegicus
Q6P4Z9
209
23217
T101
N
A
H
Q
W
S
E
T
V
Q
P
I
M
E
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507694
204
22617
P98
S
A
H
Q
W
S
E
P
I
Q
P
I
M
E
A
Chicken
Gallus gallus
NP_001041472
207
22961
T101
S
A
H
Q
W
S
E
T
V
Q
P
I
M
E
A
Frog
Xenopus laevis
Q6GQA6
195
21737
N103
S
A
Y
Q
W
S
E
N
I
Q
Q
I
M
E
A
Zebra Danio
Brachydanio rerio
Q7ZUZ0
191
21527
S99
A
A
Y
Q
W
S
E
S
I
L
P
V
M
E
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KTH8
182
21413
P94
W
S
E
R
V
K
S
P
V
E
D
L
L
N
K
Honey Bee
Apis mellifera
XP_391971
187
21201
V94
N
A
E
W
S
E
D
V
S
D
I
M
A
A
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203845
168
18975
I80
W
S
D
V
I
K
E
I
I
S
A
L
S
D
S
Poplar Tree
Populus trichocarpa
XP_002298193
199
22672
Q108
R
A
F
D
W
S
Q
Q
I
Q
P
L
V
A
A
Maize
Zea mays
NP_001141592
196
22092
D105
Q
G
F
E
W
G
P
D
L
A
D
F
I
T
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P43255
197
22528
E106
R
G
Y
D
W
S
Q
E
A
K
D
M
V
A
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.7
31.6
98
N.A.
95.2
95.6
N.A.
84.2
88
74.1
67.9
N.A.
27.2
46.8
N.A.
43.5
Protein Similarity:
100
96.6
32.2
99.5
N.A.
98
98
N.A.
91.8
93.7
85.1
77.9
N.A.
46.8
63.1
N.A.
63.1
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
80
93.3
66.6
60
N.A.
6.6
13.3
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
93.3
100
86.6
86.6
N.A.
40
26.6
N.A.
40
Percent
Protein Identity:
32.5
32.5
N.A.
33.4
N.A.
N.A.
Protein Similarity:
55.5
52.1
N.A.
53.1
N.A.
N.A.
P-Site Identity:
40
13.3
N.A.
20
N.A.
N.A.
P-Site Similarity:
66.6
33.3
N.A.
53.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
75
0
0
0
0
0
0
7
7
7
0
7
19
82
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
7
13
0
0
7
7
0
7
19
0
0
7
0
% D
% Glu:
0
0
13
7
0
7
69
7
0
7
0
0
0
63
0
% E
% Phe:
0
0
13
0
0
0
0
0
0
0
0
7
0
0
0
% F
% Gly:
0
13
0
0
0
7
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
50
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
7
0
0
7
32
0
7
57
7
0
0
% I
% Lys:
0
0
0
0
0
13
0
0
0
7
0
0
0
0
7
% K
% Leu:
0
0
0
0
0
0
0
0
7
7
0
19
7
0
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
13
63
0
0
% M
% Asn:
44
0
0
0
0
0
0
7
0
0
0
0
0
7
0
% N
% Pro:
0
0
0
0
0
0
7
13
0
0
63
0
0
0
0
% P
% Gln:
7
0
0
63
0
0
13
7
0
63
7
0
0
0
0
% Q
% Arg:
13
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
19
13
0
0
7
75
7
7
7
7
0
0
7
0
7
% S
% Thr:
0
0
0
0
0
0
0
44
0
0
0
0
0
7
0
% T
% Val:
0
0
0
7
7
0
0
7
50
0
0
7
13
0
0
% V
% Trp:
13
0
0
7
82
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
19
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _