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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EPYC All Species: 17.88
Human Site: T111 Identified Species: 49.17
UniProt: Q99645 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99645 NP_004941.2 322 36637 T111 T G V L G P H T N E D F P T C
Chimpanzee Pan troglodytes XP_509259 322 36590 T111 T G V L G P H T N E D F P T C
Rhesus Macaque Macaca mulatta XP_001102394 322 36689 T111 T G V L G P H T N E D F P T C
Dog Lupus familis XP_539714 320 36535 T109 T G V L G P H T N E D F P T C
Cat Felis silvestris
Mouse Mus musculus P70186 322 36744 T111 P G L L G P H T N E D F P T C
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512092 316 35777 L109 F P P T N E D L P A C L L C S
Chicken Gallus gallus Q90944 316 35838 L109 V P Q T Q D G L P T C L L C T
Frog Xenopus laevis NP_001087337 318 36024 C114 S G A I S P T C I L C A C L I
Zebra Danio Brachydanio rerio NP_001017903 712 74549 P492 G D I G S G I P D I D T D I Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 98.4 94.7 N.A. 82.3 N.A. N.A. 81.9 67 66.7 28.3 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 100 99.6 96.5 N.A. 89.1 N.A. N.A. 90.3 81 80.1 38.3 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 86.6 N.A. N.A. 0 0 13.3 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 93.3 N.A. N.A. 0 0 26.6 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 12 0 0 0 0 0 0 12 0 12 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 12 0 0 34 0 12 23 56 % C
% Asp: 0 12 0 0 0 12 12 0 12 0 67 0 12 0 0 % D
% Glu: 0 0 0 0 0 12 0 0 0 56 0 0 0 0 0 % E
% Phe: 12 0 0 0 0 0 0 0 0 0 0 56 0 0 0 % F
% Gly: 12 67 0 12 56 12 12 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 56 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 12 12 0 0 12 0 12 12 0 0 0 12 12 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 12 56 0 0 0 23 0 12 0 23 23 12 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 12 0 0 0 56 0 0 0 0 0 0 % N
% Pro: 12 23 12 0 0 67 0 12 23 0 0 0 56 0 0 % P
% Gln: 0 0 12 0 12 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 12 0 0 0 23 0 0 0 0 0 0 0 0 0 12 % S
% Thr: 45 0 0 23 0 0 12 56 0 12 0 12 0 56 12 % T
% Val: 12 0 45 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _