KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPYC
All Species:
34.24
Human Site:
Y243
Identified Species:
94.17
UniProt:
Q99645
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99645
NP_004941.2
322
36637
Y243
M
Y
D
L
H
H
L
Y
L
T
D
N
N
L
D
Chimpanzee
Pan troglodytes
XP_509259
322
36590
Y243
M
Y
D
L
H
H
L
Y
L
T
D
N
N
L
D
Rhesus Macaque
Macaca mulatta
XP_001102394
322
36689
Y243
M
Y
D
L
H
H
L
Y
L
T
D
N
N
L
D
Dog
Lupus familis
XP_539714
320
36535
Y241
M
Y
D
L
H
H
L
Y
L
T
D
N
N
L
D
Cat
Felis silvestris
Mouse
Mus musculus
P70186
322
36744
Y243
M
Y
D
L
H
H
L
Y
I
T
D
N
S
L
D
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512092
316
35777
Y237
M
D
D
L
H
H
L
Y
I
T
D
N
N
L
D
Chicken
Gallus gallus
Q90944
316
35838
Y237
L
H
E
L
Q
H
L
Y
I
T
D
N
N
L
D
Frog
Xenopus laevis
NP_001087337
318
36024
Y239
M
T
D
L
H
I
L
Y
L
T
N
N
H
L
N
Zebra Danio
Brachydanio rerio
NP_001017903
712
74549
Y633
M
P
G
L
L
Y
L
Y
L
T
D
N
N
I
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
98.4
94.7
N.A.
82.3
N.A.
N.A.
81.9
67
66.7
28.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
100
99.6
96.5
N.A.
89.1
N.A.
N.A.
90.3
81
80.1
38.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
86.6
N.A.
N.A.
86.6
66.6
66.6
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
93.3
93.3
86.6
80
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
12
78
0
0
0
0
0
0
0
89
0
0
0
89
% D
% Glu:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
12
0
0
78
78
0
0
0
0
0
0
12
0
0
% H
% Ile:
0
0
0
0
0
12
0
0
34
0
0
0
0
12
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
12
0
0
100
12
0
100
0
67
0
0
0
0
89
0
% L
% Met:
89
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
12
100
78
0
12
% N
% Pro:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% S
% Thr:
0
12
0
0
0
0
0
0
0
100
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
56
0
0
0
12
0
100
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _