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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: OSMR All Species: 10.91
Human Site: S780 Identified Species: 30
UniProt: Q99650 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99650 NP_003990.1 979 110509 S780 D I P D P Y K S S I L S L I K
Chimpanzee Pan troglodytes XP_001141406 979 110586 S780 D I P D P Y K S S I L S L I K
Rhesus Macaque Macaca mulatta XP_001083745 977 110407 S777 D I P D P Y K S S I L S L I K
Dog Lupus familis XP_546341 967 108830 I769 K E K C Y P D I P D P Y K S S
Cat Felis silvestris
Mouse Mus musculus O70458 971 110211 P774 C Y P D I P N P Y K S S I L S
Rat Rattus norvegicus Q65Z14 962 108606 K765 Y W K S Q W V K E K C Y P D I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507624 555 63189 S358 W K V S P I R S N P E L L C Q
Chicken Gallus gallus XP_425020 732 84442 D535 E E H V N G T D G G I L I S W
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001014328 929 102512 V732 P E I P G P K V P G N W S S P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 94.5 72.3 N.A. 55.1 57 N.A. 23.8 29 N.A. 25.5 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.6 96.9 83.8 N.A. 69.8 70.6 N.A. 37.2 41.9 N.A. 43.5 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 0 N.A. 20 0 N.A. 20 0 N.A. 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 0 N.A. 33.3 6.6 N.A. 40 20 N.A. 6.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 12 0 0 12 0 0 0 0 0 0 12 0 0 12 0 % C
% Asp: 34 0 0 45 0 0 12 12 0 12 0 0 0 12 0 % D
% Glu: 12 34 0 0 0 0 0 0 12 0 12 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 12 12 0 0 12 23 0 0 0 0 0 % G
% His: 0 0 12 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 34 12 0 12 12 0 12 0 34 12 0 23 34 12 % I
% Lys: 12 12 23 0 0 0 45 12 0 23 0 0 12 0 34 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 34 23 45 12 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 12 0 12 0 12 0 12 0 0 0 0 % N
% Pro: 12 0 45 12 45 34 0 12 23 12 12 0 12 0 12 % P
% Gln: 0 0 0 0 12 0 0 0 0 0 0 0 0 0 12 % Q
% Arg: 0 0 0 0 0 0 12 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 23 0 0 0 45 34 0 12 45 12 34 23 % S
% Thr: 0 0 0 0 0 0 12 0 0 0 0 0 0 0 0 % T
% Val: 0 0 12 12 0 0 12 12 0 0 0 0 0 0 0 % V
% Trp: 12 12 0 0 0 12 0 0 0 0 0 12 0 0 12 % W
% Tyr: 12 12 0 0 12 34 0 0 12 0 0 23 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _