Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CHP All Species: 22.73
Human Site: S99 Identified Species: 31.25
UniProt: Q99653 Number Species: 16
    Phosphosite Substitution
    Charge Score: -0.06
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99653 NP_009167.1 195 22456 S99 P I E D N E K S K D V N G P E
Chimpanzee Pan troglodytes XP_523319 364 40308 T268 V E D E D T E T Q D P K K P E
Rhesus Macaque Macaca mulatta XP_001099860 154 17969 L62 P E L A I N P L G D R I I N A
Dog Lupus familis XP_858323 176 20093 S80 E G D D N E K S K D V N G P E
Cat Felis silvestris
Mouse Mus musculus Q9D869 196 22518 L100 I D E E D A T L R D P K Q P E
Rat Rattus norvegicus P61023 195 22414 S99 P I E D N E K S K D V N G P E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520469 247 27862 S151 P I E D N E K S K D V N G P E
Chicken Gallus gallus Q5ZM44 195 22429 S99 P I E D N E K S K D Q N G P E
Frog Xenopus laevis Q5U554 214 24808 S99 M S Y F R P L S Q H M D E E N
Zebra Danio Brachydanio rerio NP_956009 194 22400 K98 R P V E D N E K N K D L T G E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24214 170 19248 I76 E V D F K E F I Q G V S Q F S
Honey Bee Apis mellifera XP_392514 189 21728 P93 Q V L A H F R P I K K N S P N
Nematode Worm Caenorhab. elegans P36608 191 22003 F85 G A I E F H E F I R A L S I T
Sea Urchin Strong. purpuratus XP_781855 190 22176 Y94 T L G L F R P Y K K R Y G P E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9C5P6 226 26010 A102 I L D F E A F A R S L S V F H
Baker's Yeast Sacchar. cerevisiae P25296 175 19620 I79 D V D F Q E F I T G L S I F S
Red Bread Mold Neurospora crassa P87072 174 19751 V79 D V D F Q E F V S G L S A F S
Conservation
Percent
Protein Identity: 100 34.8 78.9 89.7 N.A. 59.6 98.9 N.A. 78.5 96.9 32.2 89.2 N.A. 38.9 67.6 27.1 63
Protein Similarity: 100 44.2 78.9 90.2 N.A. 77.5 99.4 N.A. 78.9 97.9 49 94.8 N.A. 56.4 80 50.2 74.8
P-Site Identity: 100 20 13.3 80 N.A. 26.6 100 N.A. 100 93.3 6.6 6.6 N.A. 13.3 13.3 0 26.6
P-Site Similarity: 100 60 13.3 86.6 N.A. 46.6 100 N.A. 100 93.3 26.6 26.6 N.A. 40 33.3 13.3 33.3
Percent
Protein Identity: N.A. N.A. N.A. 22.1 37.4 39.4
Protein Similarity: N.A. N.A. N.A. 39.8 55.9 57.9
P-Site Identity: N.A. N.A. N.A. 0 6.6 6.6
P-Site Similarity: N.A. N.A. N.A. 40 33.3 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 6 0 12 0 12 0 6 0 0 6 0 6 0 6 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 12 6 36 30 18 0 0 0 0 48 6 6 0 0 0 % D
% Glu: 12 12 30 24 6 48 18 0 0 0 0 0 6 6 53 % E
% Phe: 0 0 0 30 12 6 24 6 0 0 0 0 0 24 0 % F
% Gly: 6 6 6 0 0 0 0 0 6 18 0 0 36 6 0 % G
% His: 0 0 0 0 6 6 0 0 0 6 0 0 0 0 6 % H
% Ile: 12 24 6 0 6 0 0 12 12 0 0 6 12 6 0 % I
% Lys: 0 0 0 0 6 0 30 6 36 18 6 12 6 0 0 % K
% Leu: 0 12 12 6 0 0 6 12 0 0 18 12 0 0 0 % L
% Met: 6 0 0 0 0 0 0 0 0 0 6 0 0 0 0 % M
% Asn: 0 0 0 0 30 12 0 0 6 0 0 36 0 6 12 % N
% Pro: 30 6 0 0 0 6 12 6 0 0 12 0 0 53 0 % P
% Gln: 6 0 0 0 12 0 0 0 18 0 6 0 12 0 0 % Q
% Arg: 6 0 0 0 6 6 6 0 12 6 12 0 0 0 0 % R
% Ser: 0 6 0 0 0 0 0 36 6 6 0 24 12 0 18 % S
% Thr: 6 0 0 0 0 6 6 6 6 0 0 0 6 0 6 % T
% Val: 6 24 6 0 0 0 0 6 0 0 30 0 6 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 6 0 0 0 0 6 0 0 0 6 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _