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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CHP All Species: 22.08
Human Site: T7 Identified Species: 30.36
UniProt: Q99653 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99653 NP_009167.1 195 22456 T7 _ M G S R A S T L L R D E E L
Chimpanzee Pan troglodytes XP_523319 364 40308 H175 A M G S R S S H A A V I P D G
Rhesus Macaque Macaca mulatta XP_001099860 154 17969
Dog Lupus familis XP_858323 176 20093 T7 _ M G S R A S T L L R D E E L
Cat Felis silvestris
Mouse Mus musculus Q9D869 196 22518 H7 _ M G S R S S H I A L I P D V
Rat Rattus norvegicus P61023 195 22414 T7 _ M G S R A S T L L R D E E L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520469 247 27862 Q59 A P H P V S E Q C S A P S K R
Chicken Gallus gallus Q5ZM44 195 22429 T7 _ M G S R A S T L L R D E E I
Frog Xenopus laevis Q5U554 214 24808 H7 _ M G L S H S H S V E T R E L
Zebra Danio Brachydanio rerio NP_956009 194 22400 S7 _ M G S R A S S L L R E E D I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24214 170 19248 L7 _ M G N E T S L P M E M C S N
Honey Bee Apis mellifera XP_392514 189 21728 L7 _ M G N R S S L L L R E E E I
Nematode Worm Caenorhab. elegans P36608 191 22003 Q12 N S K L K S S Q I R D L A E Q
Sea Urchin Strong. purpuratus XP_781855 190 22176 S7 _ M G S R T S S L L Q Q E E I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9C5P6 226 26010 P24 L T C C D A D P P K V R Q N P
Baker's Yeast Sacchar. cerevisiae P25296 175 19620 D10 A A P S K I V D G L L E D T N
Red Bread Mold Neurospora crassa P87072 174 19751 D10 N T T S S V L D N I V Q G S N
Conservation
Percent
Protein Identity: 100 34.8 78.9 89.7 N.A. 59.6 98.9 N.A. 78.5 96.9 32.2 89.2 N.A. 38.9 67.6 27.1 63
Protein Similarity: 100 44.2 78.9 90.2 N.A. 77.5 99.4 N.A. 78.9 97.9 49 94.8 N.A. 56.4 80 50.2 74.8
P-Site Identity: 100 33.3 0 100 N.A. 35.7 100 N.A. 0 92.8 35.7 71.4 N.A. 21.4 64.2 13.3 64.2
P-Site Similarity: 100 46.6 0 100 N.A. 64.2 100 N.A. 13.3 100 42.8 100 N.A. 35.7 92.8 33.3 85.7
Percent
Protein Identity: N.A. N.A. N.A. 22.1 37.4 39.4
Protein Similarity: N.A. N.A. N.A. 39.8 55.9 57.9
P-Site Identity: N.A. N.A. N.A. 6.6 13.3 6.6
P-Site Similarity: N.A. N.A. N.A. 13.3 33.3 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 18 6 0 0 0 36 0 0 6 12 6 0 6 0 0 % A
% Cys: 0 0 6 6 0 0 0 0 6 0 0 0 6 0 0 % C
% Asp: 0 0 0 0 6 0 6 12 0 0 6 24 6 18 0 % D
% Glu: 0 0 0 0 6 0 6 0 0 0 12 18 42 48 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 65 0 0 0 0 0 6 0 0 0 6 0 6 % G
% His: 0 0 6 0 0 6 0 18 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 6 0 0 12 6 0 12 0 0 24 % I
% Lys: 0 0 6 0 12 0 0 0 0 6 0 0 0 6 0 % K
% Leu: 6 0 0 12 0 0 6 12 42 48 12 6 0 0 24 % L
% Met: 0 65 0 0 0 0 0 0 0 6 0 6 0 0 0 % M
% Asn: 12 0 0 12 0 0 0 0 6 0 0 0 0 6 18 % N
% Pro: 0 6 6 6 0 0 0 6 12 0 0 6 12 0 6 % P
% Gln: 0 0 0 0 0 0 0 12 0 0 6 12 6 0 6 % Q
% Arg: 0 0 0 0 53 0 0 0 0 6 36 6 6 0 6 % R
% Ser: 0 6 0 59 12 30 71 12 6 6 0 0 6 12 0 % S
% Thr: 0 12 6 0 0 12 0 24 0 0 0 6 0 6 0 % T
% Val: 0 0 0 0 6 6 6 0 0 6 18 0 0 0 6 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 59 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _