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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CHP All Species: 13.64
Human Site: T86 Identified Species: 18.75
UniProt: Q99653 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0.31
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99653 NP_009167.1 195 22456 T86 N F R G F M R T L A H F R P I
Chimpanzee Pan troglodytes XP_523319 364 40308 L255 F P G F V R V L A H F R P V E
Rhesus Macaque Macaca mulatta XP_001099860 154 17969 E49 E N G T L S R E D F Q R I P E
Dog Lupus familis XP_858323 176 20093 I67 N P L G D R I I N A F F P E G
Cat Felis silvestris
Mouse Mus musculus Q9D869 196 22518 L87 F A G F A R V L A Y F R P I D
Rat Rattus norvegicus P61023 195 22414 T86 N F R G F M R T L A H F R P I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520469 247 27862 T138 N F R G F M R T L A H F R P I
Chicken Gallus gallus Q5ZM44 195 22429 T86 N F R G F M R T L A H F R P I
Frog Xenopus laevis Q5U554 214 24808 E86 Y V E E I N F E E F L I I M S
Zebra Danio Brachydanio rerio NP_956009 194 22400 R85 V N F R G F M R T L A H F R P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24214 170 19248 D63 Q R V I D I F D A D G N G E V
Honey Bee Apis mellifera XP_392514 189 21728 N80 E S G N D R V N F L Q F M Q V
Nematode Worm Caenorhab. elegans P36608 191 22003 F72 A S F V F K V F D E N K D G A
Sea Urchin Strong. purpuratus XP_781855 190 22176 F81 C E S D Q I N F R Q F M K T L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9C5P6 226 26010 D89 D R V F D L F D T K N T G I L
Baker's Yeast Sacchar. cerevisiae P25296 175 19620 D66 G R I M E V F D A D N S G D V
Red Bread Mold Neurospora crassa P87072 174 19751 D66 T R M I A I F D E D G G G D V
Conservation
Percent
Protein Identity: 100 34.8 78.9 89.7 N.A. 59.6 98.9 N.A. 78.5 96.9 32.2 89.2 N.A. 38.9 67.6 27.1 63
Protein Similarity: 100 44.2 78.9 90.2 N.A. 77.5 99.4 N.A. 78.9 97.9 49 94.8 N.A. 56.4 80 50.2 74.8
P-Site Identity: 100 0 13.3 26.6 N.A. 0 100 N.A. 100 100 0 0 N.A. 0 6.6 6.6 0
P-Site Similarity: 100 0 13.3 26.6 N.A. 0 100 N.A. 100 100 0 0 N.A. 13.3 13.3 13.3 20
Percent
Protein Identity: N.A. N.A. N.A. 22.1 37.4 39.4
Protein Similarity: N.A. N.A. N.A. 39.8 55.9 57.9
P-Site Identity: N.A. N.A. N.A. 0 0 0
P-Site Similarity: N.A. N.A. N.A. 26.6 20 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 6 6 0 0 12 0 0 0 24 30 6 0 0 0 6 % A
% Cys: 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 6 0 0 6 24 0 0 24 12 18 0 0 6 12 6 % D
% Glu: 12 6 6 6 6 0 0 12 12 6 0 0 0 12 12 % E
% Phe: 12 24 12 18 30 6 30 12 6 12 24 36 6 0 0 % F
% Gly: 6 0 24 30 6 0 0 0 0 0 12 6 24 6 6 % G
% His: 0 0 0 0 0 0 0 0 0 6 24 6 0 0 0 % H
% Ile: 0 0 6 12 6 18 6 6 0 0 0 6 12 12 24 % I
% Lys: 0 0 0 0 0 6 0 0 0 6 0 6 6 0 0 % K
% Leu: 0 0 6 0 6 6 0 12 24 12 6 0 0 0 12 % L
% Met: 0 0 6 6 0 24 6 0 0 0 0 6 6 6 0 % M
% Asn: 30 12 0 6 0 6 6 6 6 0 18 6 0 0 0 % N
% Pro: 0 12 0 0 0 0 0 0 0 0 0 0 18 30 6 % P
% Gln: 6 0 0 0 6 0 0 0 0 6 12 0 0 6 0 % Q
% Arg: 0 24 24 6 0 24 30 6 6 0 0 18 24 6 0 % R
% Ser: 0 12 6 0 0 6 0 0 0 0 0 6 0 0 6 % S
% Thr: 6 0 0 6 0 0 0 24 12 0 0 6 0 6 0 % T
% Val: 6 6 12 6 6 6 24 0 0 0 0 0 0 6 24 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 6 0 0 0 0 0 0 0 0 6 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _