Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CHP All Species: 35.45
Human Site: Y32 Identified Species: 48.75
UniProt: Q99653 Number Species: 16
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99653 NP_009167.1 195 22456 Y32 H S Q I T R L Y S R F T S L D
Chimpanzee Pan troglodytes XP_523319 364 40308 H200 Q A S L L R L H H R F R A L D
Rhesus Macaque Macaca mulatta XP_001099860 154 17969 K19 E E L E E I K K E T G F S H S
Dog Lupus familis XP_858323 176 20093 Y32 H S Q I T R L Y S R F T S L D
Cat Felis silvestris
Mouse Mus musculus Q9D869 196 22518 Y32 Q A S L L R L Y H R F Q A L D
Rat Rattus norvegicus P61023 195 22414 Y32 H S Q I T R L Y S R F T S L D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520469 247 27862 Y84 H S Q I T R L Y S R F T S L D
Chicken Gallus gallus Q5ZM44 195 22429 Y32 H S Q I T R L Y S R F T S L D
Frog Xenopus laevis Q5U554 214 24808 F32 I E H L H K R F K S L S G D E
Zebra Danio Brachydanio rerio NP_956009 194 22400 Y32 H S Q I T R L Y S R F H S L D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24214 170 19248 L32 K R F R K L D L D N S G A L S
Honey Bee Apis mellifera XP_392514 189 21728 Y32 P N Q I E R L Y S R F T S L D
Nematode Worm Caenorhab. elegans P36608 191 22003 D37 W Y K G F V R D C P N G M L T
Sea Urchin Strong. purpuratus XP_781855 190 22176 Y32 P K Q I V R L Y S R F T N L D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9C5P6 226 26010 Y49 V N E I E A L Y E L F K S I S
Baker's Yeast Sacchar. cerevisiae P25296 175 19620 R35 K R F M K L D R D S S G S I D
Red Bread Mold Neurospora crassa P87072 174 19751 K35 K R F M K L D K D N S G T I E
Conservation
Percent
Protein Identity: 100 34.8 78.9 89.7 N.A. 59.6 98.9 N.A. 78.5 96.9 32.2 89.2 N.A. 38.9 67.6 27.1 63
Protein Similarity: 100 44.2 78.9 90.2 N.A. 77.5 99.4 N.A. 78.9 97.9 49 94.8 N.A. 56.4 80 50.2 74.8
P-Site Identity: 100 40 6.6 100 N.A. 46.6 100 N.A. 100 100 0 93.3 N.A. 6.6 80 6.6 73.3
P-Site Similarity: 100 66.6 6.6 100 N.A. 66.6 100 N.A. 100 100 33.3 93.3 N.A. 13.3 86.6 13.3 80
Percent
Protein Identity: N.A. N.A. N.A. 22.1 37.4 39.4
Protein Similarity: N.A. N.A. N.A. 39.8 55.9 57.9
P-Site Identity: N.A. N.A. N.A. 33.3 13.3 0
P-Site Similarity: N.A. N.A. N.A. 53.3 26.6 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 12 0 0 0 6 0 0 0 0 0 0 18 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 6 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 18 6 18 0 0 0 0 6 65 % D
% Glu: 6 12 6 6 18 0 0 0 12 0 0 0 0 0 12 % E
% Phe: 0 0 18 0 6 0 0 6 0 0 65 6 0 0 0 % F
% Gly: 0 0 0 6 0 0 0 0 0 0 6 24 6 0 0 % G
% His: 36 0 6 0 6 0 0 6 12 0 0 6 0 6 0 % H
% Ile: 6 0 0 53 0 6 0 0 0 0 0 0 0 18 0 % I
% Lys: 18 6 6 0 18 6 6 12 6 0 0 6 0 0 0 % K
% Leu: 0 0 6 18 12 18 65 6 0 6 6 0 0 71 0 % L
% Met: 0 0 0 12 0 0 0 0 0 0 0 0 6 0 0 % M
% Asn: 0 12 0 0 0 0 0 0 0 12 6 0 6 0 0 % N
% Pro: 12 0 0 0 0 0 0 0 0 6 0 0 0 0 0 % P
% Gln: 12 0 48 0 0 0 0 0 0 0 0 6 0 0 0 % Q
% Arg: 0 18 0 6 0 59 12 6 0 59 0 6 0 0 0 % R
% Ser: 0 36 12 0 0 0 0 0 48 12 18 6 59 0 18 % S
% Thr: 0 0 0 0 36 0 0 0 0 6 0 42 6 0 6 % T
% Val: 6 0 0 0 6 6 0 0 0 0 0 0 0 0 0 % V
% Trp: 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 6 0 0 0 0 0 59 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _