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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF2C All Species: 17.88
Human Site: S225 Identified Species: 39.33
UniProt: Q99661 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99661 NP_006836.2 725 81313 S225 K R A Q E Y D S S F P N W E F
Chimpanzee Pan troglodytes XP_001151337 725 81253 S225 K R A Q E Y D S S F P N W E F
Rhesus Macaque Macaca mulatta XP_001093746 706 79332 S206 K R A Q E Y D S S F P N W E F
Dog Lupus familis XP_532606 723 81259 N223 K R A Q E Y D N N F P N W E F
Cat Felis silvestris
Mouse Mus musculus Q922S8 721 81067 S221 K R A Q E Y D S S F P N W E F
Rat Rattus norvegicus Q62909 671 75553 R204 T D P I E E H R I C V C V R K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506273 959 105390 A334 K R A Q D V D A T N P N Y E I
Chicken Gallus gallus Q5ZKV8 706 79845 I197 A T N P N Y E I M C M I R D F
Frog Xenopus laevis Q91636 730 82567 T229 K R A Q D Y D T S V P N W E F
Zebra Danio Brachydanio rerio NP_001108065 689 76957 E223 Q K R G K F G E T N R S K Q F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q960Z0 805 88653 Q243 E K V A L M N Q D P G N P N W
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 95.4 91.7 N.A. 87.5 81 N.A. 41.5 54.3 62.5 49.9 N.A. 44.2 N.A. N.A. N.A.
Protein Similarity: 100 99.7 96.5 96 N.A. 92.8 86.7 N.A. 55 72.5 78.4 66.4 N.A. 60.2 N.A. N.A. N.A.
P-Site Identity: 100 100 100 86.6 N.A. 100 6.6 N.A. 53.3 13.3 80 6.6 N.A. 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 6.6 N.A. 80 26.6 93.3 53.3 N.A. 33.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 64 10 0 0 0 10 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 19 0 10 0 0 0 % C
% Asp: 0 10 0 0 19 0 64 0 10 0 0 0 0 10 0 % D
% Glu: 10 0 0 0 55 10 10 10 0 0 0 0 0 64 0 % E
% Phe: 0 0 0 0 0 10 0 0 0 46 0 0 0 0 73 % F
% Gly: 0 0 0 10 0 0 10 0 0 0 10 0 0 0 0 % G
% His: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 10 0 0 0 10 10 0 0 10 0 0 10 % I
% Lys: 64 19 0 0 10 0 0 0 0 0 0 0 10 0 10 % K
% Leu: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 10 0 0 10 0 10 0 0 0 0 % M
% Asn: 0 0 10 0 10 0 10 10 10 19 0 73 0 10 0 % N
% Pro: 0 0 10 10 0 0 0 0 0 10 64 0 10 0 0 % P
% Gln: 10 0 0 64 0 0 0 10 0 0 0 0 0 10 0 % Q
% Arg: 0 64 10 0 0 0 0 10 0 0 10 0 10 10 0 % R
% Ser: 0 0 0 0 0 0 0 37 46 0 0 10 0 0 0 % S
% Thr: 10 10 0 0 0 0 0 10 19 0 0 0 0 0 0 % T
% Val: 0 0 10 0 0 10 0 0 0 10 10 0 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 55 0 10 % W
% Tyr: 0 0 0 0 0 64 0 0 0 0 0 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _