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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IL12RB2
All Species:
10.91
Human Site:
T685
Identified Species:
30
UniProt:
Q99665
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99665
NP_001550.1
862
97135
T685
Y
P
I
A
E
E
K
T
Q
L
P
L
D
R
L
Chimpanzee
Pan troglodytes
XP_524733
862
97080
T685
Y
P
I
A
E
E
K
T
Q
L
P
L
D
R
L
Rhesus Macaque
Macaca mulatta
XP_001094235
863
97514
T686
Y
P
T
A
E
E
K
T
Q
L
P
L
D
R
L
Dog
Lupus familis
XP_849307
840
92334
P664
N
P
L
W
P
S
V
P
D
P
A
H
S
S
L
Cat
Felis silvestris
Mouse
Mus musculus
P97378
874
98178
L696
W
V
K
K
Y
P
I
L
E
E
K
I
Q
L
P
Rat
Rattus norvegicus
P40190
918
102432
M681
N
F
N
S
K
D
Q
M
Y
S
D
A
N
F
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512506
1069
114847
M885
Y
S
F
L
E
D
E
M
Q
H
H
S
D
Q
L
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001124412
881
98985
S700
K
P
E
Q
D
I
K
S
M
D
P
L
K
K
N
Zebra Danio
Brachydanio rerio
NP_001106977
792
89258
H616
H
P
S
Q
S
L
I
H
T
G
V
S
P
L
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
93.5
24.7
N.A.
66.4
24.6
N.A.
36.8
N.A.
22.1
24.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
95.2
39.6
N.A.
76
42
N.A.
50
N.A.
38.1
42.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
13.3
N.A.
0
0
N.A.
33.3
N.A.
26.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
20
N.A.
20
33.3
N.A.
53.3
N.A.
46.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
34
0
0
0
0
0
0
12
12
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
12
23
0
0
12
12
12
0
45
0
0
% D
% Glu:
0
0
12
0
45
34
12
0
12
12
0
0
0
0
0
% E
% Phe:
0
12
12
0
0
0
0
0
0
0
0
0
0
12
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
12
% G
% His:
12
0
0
0
0
0
0
12
0
12
12
12
0
0
0
% H
% Ile:
0
0
23
0
0
12
23
0
0
0
0
12
0
0
0
% I
% Lys:
12
0
12
12
12
0
45
0
0
0
12
0
12
12
0
% K
% Leu:
0
0
12
12
0
12
0
12
0
34
0
45
0
23
56
% L
% Met:
0
0
0
0
0
0
0
23
12
0
0
0
0
0
0
% M
% Asn:
23
0
12
0
0
0
0
0
0
0
0
0
12
0
12
% N
% Pro:
0
67
0
0
12
12
0
12
0
12
45
0
12
0
12
% P
% Gln:
0
0
0
23
0
0
12
0
45
0
0
0
12
12
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
34
0
% R
% Ser:
0
12
12
12
12
12
0
12
0
12
0
23
12
12
0
% S
% Thr:
0
0
12
0
0
0
0
34
12
0
0
0
0
0
12
% T
% Val:
0
12
0
0
0
0
12
0
0
0
12
0
0
0
0
% V
% Trp:
12
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
45
0
0
0
12
0
0
0
12
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _