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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CGRRF1
All Species:
14.85
Human Site:
T249
Identified Species:
46.67
UniProt:
Q99675
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99675
NP_006559.1
332
38242
T249
S
S
S
E
E
K
N
T
D
R
S
L
L
E
K
Chimpanzee
Pan troglodytes
XP_001160908
332
38283
T249
S
S
S
E
E
K
N
T
D
R
S
L
L
E
K
Rhesus Macaque
Macaca mulatta
XP_001086182
332
38217
T249
S
S
S
E
E
K
N
T
D
R
S
L
L
E
K
Dog
Lupus familis
XP_537451
332
38187
I249
P
S
P
E
E
K
S
I
D
Q
S
L
L
E
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8BMJ7
332
37881
V249
E
S
P
E
D
R
S
V
E
Q
S
L
L
E
K
Rat
Rattus norvegicus
P97587
332
37424
V249
Q
S
P
A
D
G
S
V
E
H
S
L
L
E
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001235056
342
39305
T249
T
S
P
D
E
R
S
T
D
R
R
L
L
E
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001121476
375
41667
T263
C
N
N
N
G
S
T
T
R
G
A
L
V
A
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.8
93.9
N.A.
83.7
83.7
N.A.
N.A.
76.6
N.A.
N.A.
N.A.
N.A.
28.5
N.A.
N.A.
Protein Similarity:
100
99.6
99.4
96.9
N.A.
91.8
90.3
N.A.
N.A.
86.2
N.A.
N.A.
N.A.
N.A.
45.8
N.A.
N.A.
P-Site Identity:
100
100
100
66.6
N.A.
46.6
40
N.A.
N.A.
60
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
100
100
100
80
N.A.
80
60
N.A.
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
40
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
13
0
0
0
0
0
0
13
0
0
13
0
% A
% Cys:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
13
25
0
0
0
63
0
0
0
0
0
0
% D
% Glu:
13
0
0
63
63
0
0
0
25
0
0
0
0
88
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
13
13
0
0
0
13
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
13
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
13
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
50
0
0
0
0
0
0
0
0
88
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
100
88
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
13
13
13
0
0
38
0
0
0
0
0
0
0
0
% N
% Pro:
13
0
50
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
13
0
0
0
0
0
0
0
0
25
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
25
0
0
13
50
13
0
0
0
0
% R
% Ser:
38
88
38
0
0
13
50
0
0
0
75
0
0
0
13
% S
% Thr:
13
0
0
0
0
0
13
63
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
25
0
0
0
0
13
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _