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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GPR22
All Species:
22.73
Human Site:
S144
Identified Species:
62.5
UniProt:
Q99680
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99680
NP_005286.2
433
49265
S144
T
L
D
R
Y
D
I
S
V
K
P
A
N
R
I
Chimpanzee
Pan troglodytes
XP_001164304
433
49230
S144
T
L
D
R
Y
D
I
S
V
K
P
A
N
R
I
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_848879
433
49282
S144
T
L
D
R
Y
D
I
S
V
K
P
A
N
R
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8BZL4
432
49001
S144
T
L
D
R
Y
D
I
S
V
K
P
A
N
R
I
Rat
Rattus norvegicus
P30551
444
49639
I158
S
L
E
R
Y
G
A
I
C
R
P
L
Q
S
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508927
432
48702
S144
T
L
D
R
Y
D
I
S
V
K
P
A
N
R
V
Chicken
Gallus gallus
XP_001231969
433
49163
S144
T
L
D
R
Y
D
I
S
V
K
P
A
N
R
I
Frog
Xenopus laevis
P70031
453
51139
I170
S
I
E
R
Y
S
A
I
C
N
P
L
K
S
R
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P08255
378
42639
I102
N
L
A
V
F
D
L
I
M
C
L
K
A
P
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
N.A.
98.6
N.A.
96.7
21.3
N.A.
92.3
94.4
22.7
N.A.
N.A.
20.3
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
N.A.
99.7
N.A.
98.8
42.5
N.A.
95.3
97.2
43.4
N.A.
N.A.
39.2
N.A.
N.A.
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
100
26.6
N.A.
93.3
100
20
N.A.
N.A.
20
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
100
46.6
N.A.
100
100
40
N.A.
N.A.
40
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
12
0
0
0
23
0
0
0
0
67
12
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
23
12
0
0
0
0
0
% C
% Asp:
0
0
67
0
0
78
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
23
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
12
0
0
0
0
67
34
0
0
0
0
0
0
67
% I
% Lys:
0
0
0
0
0
0
0
0
0
67
0
12
12
0
0
% K
% Leu:
0
89
0
0
0
0
12
0
0
0
12
23
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% M
% Asn:
12
0
0
0
0
0
0
0
0
12
0
0
67
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
89
0
0
12
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% Q
% Arg:
0
0
0
89
0
0
0
0
0
12
0
0
0
67
23
% R
% Ser:
23
0
0
0
0
12
0
67
0
0
0
0
0
23
0
% S
% Thr:
67
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
12
0
0
0
0
67
0
0
0
0
0
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
89
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _