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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAP3K5
All Species:
13.33
Human Site:
S668
Identified Species:
29.33
UniProt:
Q99683
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99683
NP_005914.1
1374
154537
S668
T
E
E
G
D
C
E
S
D
L
L
E
Y
D
Y
Chimpanzee
Pan troglodytes
XP_001171211
1375
154924
S669
T
E
E
G
D
C
E
S
D
S
L
E
Y
D
Y
Rhesus Macaque
Macaca mulatta
XP_001111127
1297
143635
G637
A
E
E
A
E
G
V
G
E
V
L
E
F
D
Y
Dog
Lupus familis
XP_533420
1645
181128
T939
T
E
E
G
D
C
E
T
D
S
L
E
Y
D
Y
Cat
Felis silvestris
Mouse
Mus musculus
O35099
1380
154441
G675
A
E
D
G
D
C
E
G
D
S
L
E
Y
D
Y
Rat
Rattus norvegicus
XP_001073260
1338
150427
G639
A
E
E
G
D
C
E
G
D
S
L
E
Y
D
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511920
1243
141469
Y609
K
H
K
N
I
V
Q
Y
L
G
S
F
S
E
N
Chicken
Gallus gallus
XP_419725
1260
143069
E610
R
Y
S
Q
P
L
H
E
E
I
A
L
H
K
H
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001155222
1364
153160
S657
S
D
E
N
E
C
E
S
E
A
L
E
Y
D
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477089
1363
155478
R610
R
D
K
Q
T
Q
V
R
I
A
I
K
E
V
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001202919
1288
145042
P629
T
D
M
R
E
V
Q
P
L
H
E
E
I
L
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
44.9
68
N.A.
94.1
92.7
N.A.
84.4
80.4
N.A.
71.7
N.A.
40.6
N.A.
N.A.
44.6
Protein Similarity:
100
99.4
61.3
73.1
N.A.
95.8
94.4
N.A.
87.8
87
N.A.
84.1
N.A.
58.2
N.A.
N.A.
60.7
P-Site Identity:
100
93.3
40
86.6
N.A.
73.3
80
N.A.
0
0
N.A.
60
N.A.
0
N.A.
N.A.
13.3
P-Site Similarity:
100
93.3
66.6
93.3
N.A.
80
80
N.A.
20
26.6
N.A.
86.6
N.A.
26.6
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
28
0
0
10
0
0
0
0
0
19
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
55
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
28
10
0
46
0
0
0
46
0
0
0
0
64
0
% D
% Glu:
0
55
55
0
28
0
55
10
28
0
10
73
10
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
10
10
0
0
% F
% Gly:
0
0
0
46
0
10
0
28
0
10
0
0
0
0
0
% G
% His:
0
10
0
0
0
0
10
0
0
10
0
0
10
0
10
% H
% Ile:
0
0
0
0
10
0
0
0
10
10
10
0
10
0
0
% I
% Lys:
10
0
19
0
0
0
0
0
0
0
0
10
0
10
0
% K
% Leu:
0
0
0
0
0
10
0
0
19
10
64
10
0
10
10
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
19
0
0
0
0
0
0
0
0
0
0
10
% N
% Pro:
0
0
0
0
10
0
0
10
0
0
0
0
0
0
10
% P
% Gln:
0
0
0
19
0
10
19
0
0
0
0
0
0
0
0
% Q
% Arg:
19
0
0
10
0
0
0
10
0
0
0
0
0
0
0
% R
% Ser:
10
0
10
0
0
0
0
28
0
37
10
0
10
0
0
% S
% Thr:
37
0
0
0
10
0
0
10
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
19
19
0
0
10
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
0
10
0
0
0
0
55
0
64
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _