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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GFI1 All Species: 6.06
Human Site: Y25 Identified Species: 12.12
UniProt: Q99684 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99684 NP_001120687.1 422 45297 Y25 P R S P G P D Y S L R L E N V
Chimpanzee Pan troglodytes A2T736 578 65733 H114 L Q T L V K E H Q L E N G E E
Rhesus Macaque Macaca mulatta XP_001099294 422 45259 Y25 P R S P G S D Y S L R L E N V
Dog Lupus familis XP_548402 327 37145
Cat Felis silvestris
Mouse Mus musculus P70338 423 45856 S26 R S P G P D Y S L R L E T V P
Rat Rattus norvegicus Q07120 423 45839 S26 R S P G P D Y S L R L E T V P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511538 384 43559 H18 G S T N S Y E H L T C S T V S
Chicken Gallus gallus O42409 337 38668
Frog Xenopus laevis Q6DCW1 343 39209
Zebra Danio Brachydanio rerio Q804Q5 430 47522 S28 G A T A A P K S L A F S I D R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9N658 541 61288 L107 Q R D R D F A L T P E K E H E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_793846 563 62216 Y25 Y A L S P S E Y S D E S S P A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 26.1 99.5 49.2 N.A. 87.4 87.4 N.A. 46.2 50 48.5 28.6 N.A. 30.3 N.A. N.A. 38.7
Protein Similarity: 100 38.5 99.5 58 N.A. 91.2 91.4 N.A. 55.9 59 58 41.6 N.A. 40.4 N.A. N.A. 47
P-Site Identity: 100 6.6 93.3 0 N.A. 0 0 N.A. 0 0 0 6.6 N.A. 13.3 N.A. N.A. 13.3
P-Site Similarity: 100 33.3 93.3 0 N.A. 0 0 N.A. 20 0 0 20 N.A. 26.6 N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 17 0 9 9 0 9 0 0 9 0 0 0 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % C
% Asp: 0 0 9 0 9 17 17 0 0 9 0 0 0 9 0 % D
% Glu: 0 0 0 0 0 0 25 0 0 0 25 17 25 9 17 % E
% Phe: 0 0 0 0 0 9 0 0 0 0 9 0 0 0 0 % F
% Gly: 17 0 0 17 17 0 0 0 0 0 0 0 9 0 0 % G
% His: 0 0 0 0 0 0 0 17 0 0 0 0 0 9 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % I
% Lys: 0 0 0 0 0 9 9 0 0 0 0 9 0 0 0 % K
% Leu: 9 0 9 9 0 0 0 9 34 25 17 17 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 9 0 0 0 0 0 0 0 9 0 17 0 % N
% Pro: 17 0 17 17 25 17 0 0 0 9 0 0 0 9 17 % P
% Gln: 9 9 0 0 0 0 0 0 9 0 0 0 0 0 0 % Q
% Arg: 17 25 0 9 0 0 0 0 0 17 17 0 0 0 9 % R
% Ser: 0 25 17 9 9 17 0 25 25 0 0 25 9 0 9 % S
% Thr: 0 0 25 0 0 0 0 0 9 9 0 0 25 0 0 % T
% Val: 0 0 0 0 9 0 0 0 0 0 0 0 0 25 17 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 9 0 0 0 0 9 17 25 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _