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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MGLL
All Species:
23.33
Human Site:
S196
Identified Species:
46.67
UniProt:
Q99685
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99685
NP_001003794.1
303
33261
S196
T
E
V
D
I
Y
N
S
D
P
L
I
C
R
A
Chimpanzee
Pan troglodytes
XP_001140395
142
15737
R43
E
I
G
L
A
Y
G
R
L
K
V
C
F
G
I
Rhesus Macaque
Macaca mulatta
XP_001099193
305
33406
S198
T
E
V
D
I
Y
N
S
D
P
L
I
C
R
A
Dog
Lupus familis
XP_856683
304
33364
S196
T
E
V
D
L
Y
N
S
D
P
L
I
C
R
A
Cat
Felis silvestris
Mouse
Mus musculus
O35678
303
33369
S196
S
E
V
D
L
Y
N
S
D
P
L
V
C
R
A
Rat
Rattus norvegicus
Q8R431
303
33481
S196
S
E
V
D
L
Y
N
S
D
P
L
I
C
H
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506833
303
33102
A196
T
E
V
D
S
Y
N
A
D
S
L
V
C
H
A
Chicken
Gallus gallus
XP_414365
303
33320
S196
K
E
M
E
S
Y
T
S
D
P
L
V
Y
H
G
Frog
Xenopus laevis
NP_001087903
309
34182
T196
K
E
I
E
A
Y
T
T
D
P
L
V
Y
H
G
Zebra Danio
Brachydanio rerio
NP_956591
300
33642
K196
K
Q
V
E
A
Y
E
K
D
E
L
N
Y
H
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798605
323
35764
G190
K
D
P
L
V
W
H
G
G
V
K
A
R
W
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P28321
313
35531
A197
T
S
D
K
A
Y
R
A
F
L
G
S
D
P
M
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
39.9
88.8
92.7
N.A.
84.1
83.8
N.A.
86.8
69.9
59.5
56.1
N.A.
N.A.
N.A.
N.A.
37.7
Protein Similarity:
100
41.5
91.4
96.7
N.A.
93.4
92.4
N.A.
95.3
85.1
78.6
70.9
N.A.
N.A.
N.A.
N.A.
51
P-Site Identity:
100
6.6
100
93.3
N.A.
80
80
N.A.
66.6
40
33.3
26.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
13.3
100
100
N.A.
100
93.3
N.A.
80
60
60
40
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
45
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
34
0
0
17
0
0
0
9
0
0
59
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
9
50
0
0
% C
% Asp:
0
9
9
50
0
0
0
0
75
0
0
0
9
0
0
% D
% Glu:
9
67
0
25
0
0
9
0
0
9
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
9
0
0
0
9
0
0
% F
% Gly:
0
0
9
0
0
0
9
9
9
0
9
0
0
9
25
% G
% His:
0
0
0
0
0
0
9
0
0
0
0
0
0
42
0
% H
% Ile:
0
9
9
0
17
0
0
0
0
0
0
34
0
0
9
% I
% Lys:
34
0
0
9
0
0
0
9
0
9
9
0
0
0
0
% K
% Leu:
0
0
0
17
25
0
0
0
9
9
75
0
0
0
0
% L
% Met:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
9
% M
% Asn:
0
0
0
0
0
0
50
0
0
0
0
9
0
0
0
% N
% Pro:
0
0
9
0
0
0
0
0
0
59
0
0
0
9
0
% P
% Gln:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
9
9
0
0
0
0
9
34
0
% R
% Ser:
17
9
0
0
17
0
0
50
0
9
0
9
0
0
0
% S
% Thr:
42
0
0
0
0
0
17
9
0
0
0
0
0
0
0
% T
% Val:
0
0
59
0
9
0
0
0
0
9
9
34
0
0
0
% V
% Trp:
0
0
0
0
0
9
0
0
0
0
0
0
0
9
0
% W
% Tyr:
0
0
0
0
0
92
0
0
0
0
0
0
25
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _