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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MGLL All Species: 32.12
Human Site: Y58 Identified Species: 64.24
UniProt: Q99685 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99685 NP_001003794.1 303 33261 Y58 A G E H S G R Y E E L A R M L
Chimpanzee Pan troglodytes XP_001140395 142 15737
Rhesus Macaque Macaca mulatta XP_001099193 305 33406 Y58 A G E H C G R Y E E L A Q M L
Dog Lupus familis XP_856683 304 33364 Y58 A G E H C G R Y D E L A Q M L
Cat Felis silvestris
Mouse Mus musculus O35678 303 33369 Y58 A G E H C G R Y D E L A H M L
Rat Rattus norvegicus Q8R431 303 33481 Y58 A G E H C G R Y D E L A Q M L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506833 303 33102 Y58 A G E H S G R Y E D L A Q M L
Chicken Gallus gallus XP_414365 303 33320 Y58 A G E H C G R Y D D L A Q R L
Frog Xenopus laevis NP_001087903 309 34182 Y58 A G E H C C R Y D D L A Q I L
Zebra Danio Brachydanio rerio NP_956591 300 33642 Y58 A G E H C G G Y A D I A H S L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798605 323 35764 G58 A A S F T K L G C L V Y G H D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P28321 313 35531 L59 Y T K I Q F R L M D H L S L N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 39.9 88.8 92.7 N.A. 84.1 83.8 N.A. 86.8 69.9 59.5 56.1 N.A. N.A. N.A. N.A. 37.7
Protein Similarity: 100 41.5 91.4 96.7 N.A. 93.4 92.4 N.A. 95.3 85.1 78.6 70.9 N.A. N.A. N.A. N.A. 51
P-Site Identity: 100 0 86.6 80 N.A. 80 80 N.A. 86.6 66.6 60 53.3 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 0 93.3 93.3 N.A. 86.6 93.3 N.A. 100 86.6 86.6 66.6 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 23.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 45 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 84 9 0 0 0 0 0 0 9 0 0 75 0 0 0 % A
% Cys: 0 0 0 0 59 9 0 0 9 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 42 42 0 0 0 0 9 % D
% Glu: 0 0 75 0 0 0 0 0 25 42 0 0 0 0 0 % E
% Phe: 0 0 0 9 0 9 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 75 0 0 0 67 9 9 0 0 0 0 9 0 0 % G
% His: 0 0 0 75 0 0 0 0 0 0 9 0 17 9 0 % H
% Ile: 0 0 0 9 0 0 0 0 0 0 9 0 0 9 0 % I
% Lys: 0 0 9 0 0 9 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 9 9 0 9 67 9 0 9 75 % L
% Met: 0 0 0 0 0 0 0 0 9 0 0 0 0 50 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 9 0 0 0 0 0 0 0 50 0 0 % Q
% Arg: 0 0 0 0 0 0 75 0 0 0 0 0 9 9 0 % R
% Ser: 0 0 9 0 17 0 0 0 0 0 0 0 9 9 0 % S
% Thr: 0 9 0 0 9 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 9 0 0 0 0 0 0 75 0 0 0 9 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _